Results 31 to 40 of about 669,627 (316)
FAK-inhibition opens the door to checkpoint immunotherapy in Pancreatic Cancer
Immunotherapy has had remarkable success in the treatment of some cancer types. However, pancreatic cancer has remained largely refractory to immunotherapy, including immune checkpoint inhibitors.
Stefan N. Symeonides +2 more
doaj +1 more source
A new musculoskeletal reconstruction and revision of the cranio‐mandibular anatomy of the Devonian arthrodire placoderm Dunkleosteus terrelli from a comparative and functional anatomical perspective. Dunkleosteus is a specialized arthrodire with many specializations for feeding on large vertebrates, and many of its features are part of broader ...
Russell K. Engelman +4 more
wiley +1 more source
Background Allogeneic hematopoietic stem cell transplantation and checkpoint blockade therapy are immune-based therapies that have activity in selected refractory hematologic malignancies.
Justin Kline +4 more
doaj +1 more source
Abstract The study of morphological evolution is fundamentally tied to ontogeny, yet studies of these heterochronic processes in the fossil record are rare. Fossils belonging to an ontogenetic series are difficult to assign to an ontogenetic stage due to inconsistent proxies for skeletal ages, challenging to taxonomically assign due to morphological ...
Erika R. Goldsmith, Michelle R. Stocker
wiley +1 more source
Martiodrilus Michaelsen, 1936 1936
Genus Martiodrilus Michaelsen, 1936 Martiodrilus Michaelsen, 1936: 1172. — Righi 1971: 4; 1995: 512. — Zicsi & Csuzdi 1997: 82. — Zicsi 2001: 113. — Csuzdi & Pavlíček 2011: 57. Thamnodrilus – Michaelsen 1900: 434. — Černosvitov 1935: 18. Thamnodrilus (Thamnodrilus) (part.) — Michaelsen 1918: 86. — Černosvitov 1934: 53.
Decaëns, Thibaud +9 more
openaire +1 more source
Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille +6 more
wiley +1 more source
Was ist Bibliothekswissenschaft
Erstabdruck in Vereinigung schweizerischer Bibliothekare Nachrichten 12 (1936) 3–7 12. Jg. (1936), Nr. 3, S. 15–21 https://doi.org/10.5169/seals-770479 12. Jg. (1936), Nr. 4, S. 23–28 https://doi.org/10.5169/seals-770480 12. Jg. (1936), Nr. 5, S.
Hans Lutz
doaj +1 more source
Abstract The ray‐finned fishes include one out of every two species of living vertebrates on Earth and have an abundant fossil record stretching 380 million years into the past. The division of systematic knowledge of ray‐finned fishes between paleontologists working on extinct animals and neontologists studying extant species has obscured the ...
Jack Stack
wiley +1 more source
Nasal soft‐tissue anatomy of Triceratops and other horned dinosaurs
Abstract Although ceratopsid dinosaurs possess a characteristically hypertrophied narial region, soft‐tissue anatomy associated with such a skeletal structure and their biological significance remain poorly understood. The present study provides the first comprehensive hypothesis on the soft‐tissue anatomy in the ceratopsid rostrum based on the Extant ...
Seishiro Tada +5 more
wiley +1 more source
Abstract The middle Permian represents a critical interval in therapsid evolution, when gorgonopsians emerged as some of the first specialized apex predators within terrestrial ecosystems. Despite their significance, the early diversification of Gorgonopsia in Gondwana remains poorly understood due to scarcity and fragmentary material.
Zanildo Macungo +5 more
wiley +1 more source

