Results 241 to 250 of about 411,311 (295)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Analysis of the Thermal Oxidation of Biodiesel with and without Coffee Leaf Extract Using Nuclear Magnetic Resonance (¹H NMR). [PDF]

ACS Omega
Mantovani ACG, Romagnoli ÉS, Gonçales Filho J, Sartor RA, Branco IG, Tupan LFS, Valezi DF, Mincache AJ, Borsato D, Angilelli KB.   +9 more
europepmc   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Untargeted ¹H NMR-based metabolomics unveils distinct circulating biochemical signatures between treatment-resistant and non-treatment-resistant schizophrenia patients: a pilot study. [PDF]

Transl Psychiatry
Marino C, Zhang S, De Simone G, Grimaldi M, Di Maio A, Iasevoli F, Errico F, D'Ursi AM, de Bartolomeis A, Usiello A.   +9 more
europepmc   +1 more source

Rewriting Polymer Fate via Chemomechanical Coupling

Advanced Materials, EarlyView.
This work introduces a life‐like “living” polymer platform that can grow, degrow, and reprogram its properties after fabrication. By integrating mass transport, reversible polymerization, and controlled catalysis, the material achieves on‐demand changes in size, shape, and mechanical properties.
Jiahe Huang, Haohui Zhang, Jiehao Chen, Xuelin Sui, Febby Krisnadi, Dongjing He, Huajian Ji, Will R. Gutekunst, Michael D. Dickey, Yuhang Hu   +9 more
wiley   +1 more source

Urinary ¹H-NMR Metabolomics Highlights MIIA (Microbiota-Immune-Inflammation Axis) Activation by Organic Mediterranean Diet. [PDF]

Metabolites
Di Renzo L, Cesaroni S, Frank G, Pala B, Cicero DO, Gualtieri P, Petrella G.   +6 more
europepmc   +1 more source

Accurate Protein Dynamic Conformational Ensembles: Combining AlphaFold, MD, and Amide ¹⁵N(¹H) NMR Relaxation. [PDF]

Int J Mol Sci
Lesovoy D, Roshchin K, Sala BM, Sandalova T, Achour A, Agback T, Agback P, Orekhov V.   +7 more
europepmc   +1 more source

Potential Nutraceuticals in Mussel Waste [PDF]

, 2012
Neil, D.M., Thompson, J.
core  

The lysine degradation pathway analyzed with ¹H-NMR-targeted metabolomics of MG63 cells on poly(l-lactide)-based scaffolds. [PDF]

RSC Adv
Ziblim Z, Liu Z, Thapsukhon B, Jaikang C, Konguthaithip G, Choommongkol V, Boonyawan D, Ruangsuriya J.   +7 more
europepmc   +1 more source

Time-series metabolomic profiling of SARS-CoV-2 infection: Possible prognostic biomarkers in patients in the ICU by ¹H-NMR analysis. [PDF]

PLoS One
Matpan E, Baykal AT, Telci L, Kundak T, Serteser M.   +4 more
europepmc   +1 more source