Results 21 to 30 of about 411,311 (295)

Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]

, 2013
The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E., Arrowsmith J., Barvaux V. A., Boberg F., Boyd M. R., Bunz F., Damera K., Darkes M. J. M., De K., Denny B. J., Dimitrios Pletsas, Dinca E. B., Elrashied A. E. Garelnabi, Garelnabi E. A. E., Hirose Y., Honnalli S. S., Judson P. L., Karran P., Karran P., Kotera M., Leteurtre F., Li Li, Liu L., McElhinney R. S., McGarrity J. F., Mladek A. C., Nishizuka S., Pletsas D., Richard T. Wheelhouse, Roger M. Phillips, Sarkaria J. N., Schmidt B. F., Schmiedekamp A., Shealy Y. F., Siddiqui A. A., Smith R. H., Stevens M. F. G., Svilar D., Wang Y., Wheelhouse R. T., Wheelhouse R. T., Zhang J., Zhang J.   +42 more
core   +1 more source

Structural Elucidation and NMR Spectral Assignments of Two C19-Diterpenoid Alkaloids

Chinese Journal of Magnetic Resonance, 2018
Two C19-diterpenoid alkaloids, homochasmanine (compound 1) and 14-debenzoylfranchetine (compound 2), were isolated from the roots of Aconitum handelianum. Their structures were elucidated by one-dimensional and two-dimensional nuclear magnetic resonance (
YIN Tian-peng, CHEN Yang, LUO Ping, CAL Le, DING Zhong-tao   +4 more
doaj   +1 more source

Addition of Di(trimethylsilyl) Phosphite to Schiff Bases of 2,5-Diformylfuran [PDF]

, 2011
A series of 2,5-Furanyl-bis-(aminomethylphosphonic Acids) has been synthesized by the addition of di(trimethylsilyl) phosphite to azomethine bond of achiral Schiff bases derved from 2,5-diformylfuran.
Ciechańska, Magdalena, Dzięgielewski, Marek, Lewkowski, Jarosław, Szcześniak, Aleksandra   +3 more
core   +1 more source

Synthesis of Optically Active Bifunctional Building Blocks through Enantioselective Copper-Catalyzed Allylic Alkylation Using Grignard Reagents [PDF]

, 2007
Enantioselective copper-catalyzed allylic alkylations were performed on allylic bromides with a protected hydroxyl or amine functional group using several Grignard reagents and Taniaphos L1 as a ligand.
Feringa, Ben L.,, López, Fernando,, Minnaard, Adriaan J.,, Zijl, Anthoni W. van,   +3 more
core   +1 more source

An NMR Study of N-isobutyryl-3'-O-(1-fluoro-1,1,3,3-tetraisopropyl-1,3-disiloxane-3-yl)-2'-benzyloxycarbonyl-guanosine

Chinese Journal of Magnetic Resonance, 2019
The nucleoside derivative N-isobutyryl-3'-O-(1-fluoro-1,1,3,3-tetraisopropyl-1,3-disiloxane-3-yl)-2'-benzyloxy carbonyl-guanosine (compound 1) was obtained by selectively cleaving the 1,1,3,3-tetraisopropyldisiloxanyl protecting group at 5'-position with
WEI Hui-qiang, YU Jiang, BI Chang-fen, NING Hong-xin, LI Yi-liang, LIU Qiang   +5 more
doaj   +1 more source

The solvation and dissociation of 4-benzylaniline hydrochloride in chlorobenzene [PDF]

, 2014
A reaction scheme is proposed to account for the liberation of 4-benzylaniline from 4-benzylaniline hydrochloride, using chlorobenzene as a solvent at a temperature of 373 K.
Alice A. Miller, Amrute A. P., Archie Eaglesham, Badawi H., Ball D. W., Brock F. H., Burkus J., Cavani F., David Adam, David Lennon, Di Giacomo A., Ding J., Dunlap K. L., Emma K. Gibson, Fogg P. G. T., Freeman R., Frost A. A., Gibson E. K., Gibson E. K., Guéron M., Hevia M. A. G., John M. Winfield, Khairuzzaman A., López N., Mitchell C. J., Mondelli C., Over H., Randall D., Richter R. H., Robert H. Carr, Serajuddin A. T. M., Silkov A. A., Sun S., Sutherland I. W., Tebutt P., Ulrich H., Ulrich H., Yang P. F., Zhang T., Zhang T., Zhang T.   +40 more
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1H NMR relaxation in urea

Journal of Molecular Structure, 2007
Abstract Proton NMR spin–lattice relaxation times T1 were measured for urea as a function of temperature. An activation energy of 46.3 ± 4.7 kJ/mol was extracted and compared with the range of 38–65 kJ/mol previously reported in the literature as measured by different magnetic resonance techniques.
Taylor, Robert E, Bacher, Alfred D, Dybowski, C.   +2 more
openaire   +3 more sources

Heterobimetallic Complexes of Rhenium and Zinc: Potential Catalysts for Homogeneous Syngas Conversion [PDF]

, 2011
6-(Diphenylphosphino)-2,2′-bipyridine (PNN) coordinates to rhenium carbonyls in both κ^1(P) and κ^2(N,N) modes; in the former, the free bpy moiety readily binds to zinc alkyls and halides.
Bercaw, John E., Labinger, Jay A., West, Nathan M.   +2 more
core   +2 more sources

Spectral data of nicotabaflavonoidglycoside

Data in Brief, 2018
The dataset addressed in this article relates to the research article entitled“Nicotabaflavonoidglycoside, the first example of cembranoid and flavonoid heterodimer from Nicotiana tabacum” (Yang et al., 2018) [1]. The dataset presents the MS4(879-571-421-
Cai-Yan Yang, Yao Lin, Hui-Xiong Yuan, Wen-Pei Yang, Xian Wei, Zu-Liang Huang   +5 more
doaj   +1 more source

Structure and Reactivity of Half-Sandwich Rh(+3) and Ir(+3) Carbene Complexes. Catalytic Metathesis of Azobenzene Derivatives [PDF]

, 2018
Traditional rhodium carbene chemistry relies on the controlled decomposition of diazo derivatives with [Rh2(OAc)4] or related dinuclear Rh(+2) complexes, whereas the use of other rhodium sources is much less developed.
Farès, C., Fürstner, A., Goddard, R., Philipps, P., Tindall, D., Werlé, C.   +5 more
core   +1 more source