Results 31 to 40 of about 1,079,697 (312)

Microwave-Assisted Regioselective Synthesis and 2D-NMR Studies of New 1,2,3-Triazole Compounds Derived from Acridone

Journal of Chemistry, 2021
A simple and mild protocol towards the synthesis of new 1,2,3-triazole compounds derived from acridone has been developed via regiospecific 1,3-dipolar cycloaddition reaction between 10-(prop-2-yn-1-yl)acridone derivatives and aromatic azides using CuI ...
Mohammed Aarjane, Siham Slassi, Bouchra Tazi, Amina Amine   +3 more
doaj   +1 more source

Combined use of 1H-NMR and GC-MS for metabolite monitoring and in vivo 1H-NMR assignments

Biochimica et Biophysica Acta (BBA) - General Subjects, 1986
Thirty-three metabolites were observed in perchloric acid extracts of four different tissues by in vitro 1H-NMR, GC-MS and alcohol dehydrogenase assay, and the information was used to interpret an in vivo two-dimensional nuclear Overhauser effect 1H-NMR spectrum.
T W, Fan, R M, Higashi, A N, Lane, O, Jardetzky   +3 more
openaire   +2 more sources

Quantification of drugs encapsulated in liposomes by 1H NMR [PDF]

Colloids and Surfaces B: Biointerfaces, 2019
Liposomes are one of the most important and extensively studied drug delivery system due to their ability to encapsulate different kinds of drugs. Exploiting the advantages of 1H Nuclear Magnetic Resonance (NMR) spectrometry, we established a rapid and easy method for quantification of drugs encapsulated in liposomes.
Guimarães, Diana, Noro, Jennifer, Loureiro, Ana, Cavaco-Paulo, Artur, Nogueira, Eugénia   +4 more
openaire   +3 more sources

Spectral Analysis of Glucose-Based Chiral N-heterocyclic Carbene Precursors

Chinese Journal of Magnetic Resonance, 2018
1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-3-butylimidazolium bromide (compound 2) was synthesized with 1-bromobutane and 1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl) imidazole (compound 1), which is a glucose-derived chiral N-heterocyclic carbene ...
ZHOU Zhong-gao, YUAN Yang-yang, HUANG Li, LIU Jin-xiang, XIE Yong-rong   +4 more
doaj   +1 more source

1H-NMR based lipid profiling of Gossypium hirsutum seed oil at different developmental stages

Current Research in Green and Sustainable Chemistry, 2021
1H-NMR spectroscopy is emerging as powerful robust analytical technique in analyzing bio constituents present in plants. It offers non-invasive method for identification and quantification of several Phyto-constitutes in a single step without much pre ...
Nikita J. Kurkuri, Sanjay Annarao, Prashanth Miyapadavu, Jayalakshmi Kamaiah   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

NMR Characterization of Flavanone Naringenin 7-O-Glycoside Diastereomer

Chinese Journal of Magnetic Resonance, 2017
To discriminate R and S flavanone glycoside using NMR, the mixture of R and S naringenin 7-O-glycoside was first isolated from Gleditsia sinensis. 1H and 13C NMR data of the mixture were recorded with 1H NMR, 13C NMR, 1H-1H COSY, 1H-13C HSQC and 1H-13C ...
SUN Li-juan, HU Xiao-fang, CHENG Xun, LUO Li-ting, LIU Hong-bing, CHEN Lei   +5 more
doaj   +1 more source

Barriers to resolution in 1H NMR of rotating solids

Journal of Magnetic Resonance, 2023
The role of 1H solid-state NMR in structure elucidation of solids is becoming more preponderant, particularly as faster magic-angle spinning rates (MAS) become available which improve 1H detected assignment strategies. However, current 1H spectral resolution is still relatively poor, with linewidths of typically a few hundred Hz, even at the fastest ...
Bruno, Simões de Almeida, Daria, Torodii, Pinelopi, Moutzouri, Lyndon, Emsley   +3 more
openaire   +2 more sources

Positional Enrichment by Proton Analysis (PEPA): A One‐Dimensional 1H‐NMR Approach for 13C Stable Isotope Tracer Studies in Metabolomics

Angewandte Chemie, 2017
A novel metabolomics approach for NMR‐based stable isotope tracer studies called PEPA is presented, and its performance validated using human cancer cells.
M. Vinaixa, M. Rodriguez, Suvi Aivio, Jordi Capellades, J. Gómez, N. Canyellas, T. Stracker, Ó. Yanes   +7 more
semanticscholar   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source