Results 131 to 140 of about 7,321,433 (323)

Bassein [cartographic material] /

open access: yes, 1945
1st ed. Feb 1945. Map of Bassein and surrounding area showing transportation, ground and water features, religious and other buildings.; Standard map series designation: [Series] HIND 1036.; "Refer to this map as:- HIND 1036 Bassein first edition".; Also
Great Britain. Army. Indian Field Survey Company, 1st.
core  

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

open access: yesAdvanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao   +19 more
wiley   +1 more source

First-Gen Faculty Voices

open access: yes, 2023
Prof. Randy Kozel Prof. Stephen Smith Prof. Nicole Garnett Prof. Sadie Blanchard Prof.
1st Generation Professionals
core   +1 more source

Associations between immigration background, adverse childhood experiences, and depressive symptoms in adulthood in immigrants and descendants of immigrants in France: a mediation analysis

open access: yesAnnals of General Psychiatry
Introduction In France, 10% of the population are immigrants and another 11% are children of immigrants. Both have worse mental health than the native French.
Kasra Zarei   +7 more
doaj   +1 more source

A Real‐Data‐Driven Framework for Evaluating Differential Transcript Usage Methods Across Long‐Read Bulk, Single‐Cell, and Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Grounded in real biological RNA‐seq data, the framework benchmarks ten differential transcript usage (DTU) methods across short‐read bulk, long‐read bulk, long‐read single‐cell, and long‐read spatial transcriptomics. By integrating reference transcript sets with ranked DTU results, the Transcript Set Enrichment Score (TSES) identifies data‐type ...
Chenxing Zhang   +6 more
wiley   +1 more source

Integration of 1st and 2nd Generation Bioethanol Fuel Production: Opportunities and Limitations

open access: yesBioResources
Bioethanol currently is the most widely used transport biofuel in the world. At present, it is mainly produced from starch-rich grains and sugar cane (the first generation bioethanol fuel).
Zhanye Xv   +4 more
doaj  

Synergistic Effects in Multistate Black Electro‐Thermochromic Smart Windows for Energy‐Efficient Modulation of Solar Heating

open access: yesAdvanced Science, EarlyView.
Hybrid electro‐thermochromic smart windows are developed for dynamic climate control by integrating a redox‐matched black electrochromic gel with a paraffin‐based thermochromic film. This synergistic combination enables multimodal solar modulation, where photothermal heating from the electrochromic layer triggers thermochromic activation at lower ...
Xilu Wu   +12 more
wiley   +1 more source

Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice

open access: yesAdvanced Science, EarlyView.
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang   +12 more
wiley   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

open access: yesAdvanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang   +16 more
wiley   +1 more source

Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node‐Targeting and Augments mRNA Vaccine Efficacy

open access: yesAdvanced Science, EarlyView.
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha   +5 more
wiley   +1 more source

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