Results 121 to 130 of about 286 (167)

Synthesis and Herbicidal Activity of 3-Acetyl-4-hydroxy-2,1-benzothiazine Derivatives

Chemical Research in Chinese Universities, 2019
In order to develop a novel herbicide containing the 2,1-benzothiazine motif, a series of 3-acetyl-4-hydroxy-2,1-benzothiazine derivatives was synthesized. All the target compounds were confirmed by 1H NMR, 13C NMR, and high-resolution mass spectrometry(HRMS).
Kang Lei, Yang Liu, Shiben Wang, Bin Sun, Xuewen Hua, Xiaohua Xu   +5 more
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A convenient synthesis of 3,4-dihydro-2,2-dioxide 5-hydroxy-2,1-benzothiazine

Tetrahedron Letters, 1994
Abstract 3-methoxy-2-methyl-aniline 3 is converted to the benzothiazine-dioxide 1 in a 7-steps procedure: the key transformation being the cyclization of an ortho-functionnalized N-benzyl sulfonanilide.
Dominique Blondet, Jean-Claude Pascal
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Synthesis, antiinflammatory, and cytotoxic activity of novel pyrazolo[4,3‐c][2,1]benzothiazine 4,4‐dioxide derivatives

Journal of Heterocyclic Chemistry, 2022
Abstract13 novel pyrazolo[4,3‐c][2,1]benzothiazine 4,4‐dioxide derivatives that mimic the pharmacophore of piroxicam as well as celecoxib were conveniently synthesized in a catalyst‐free and atom‐economical method in which an unconventional redox‐neutral reaction of 2‐nitrochalcones with elemental sulfur to straightforward access to 2,1‐benzothiazine 2,
Ngoc Binh Vo, Quoc Anh Ngo
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1,2- and 2,1-Benzothiazines and Related Compounds

1981
Publisher Summary The chapter focuses primarily on the two ring systems 1 and 2 and their oxidized derivatives. A few related ring systems, such as dibenzo- and hetero ring-fused 1,2-thiazines are included where it appears appropriate because of similar chemistry or analogous utility to the benzothiazine compounds. This chapter brings together all of
J.G. Lombardino, D.E. Kuhla
openaire   +1 more source

Recent advancement in the synthesis of 1,2- and 2,1-benzothiazines

Synthetic Communications, 2018
1,2- and 2,1-benzothiazines, for example, 1,2-benzothiazine-1,1-dioxides. 2,benzothiazine-2,2-dioxides, 1-alkyl/aryl-1,2-/2,1-benzothiazine-S-oxides, dibenzothiazine and polyheterocycle containing ...
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Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase

European Journal of Medicinal Chemistry, 2018
Over recent years, many RNA viruses have been "re-discovered", including life-threatening flaviviruses, such as Dengue, Zika, and several encephalitis viruses. Since no specific inhibitors are currently available to treat these infections, there is a pressing need for new therapeutics.
Rolando Cannalire, Delia Tarantino, Andrea Astolfi, Maria Letizia Barreca, Stefano Sabatini, Serena Massari, Oriana Tabarrini, Mario Milani, Gilles Querat, Eloise Mastrangelo, Giuseppe Manfroni, Violetta Cecchetti   +11 more
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Chapter 1 Recent progress in the chemistry of 2,1-benzothiazines

2008
Publisher Summary This chapter discusses the progress of synthetic procedures and applications of 2,1-benzothiazines and related compounds. Togo's group reported the preparation of the 2,1-benzothiazines via an ionic pathway with hypervalent iodine compounds.
Xuechuan Hong, Michael Harmata
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2,1-Benzothiazine 2,2-Dioxides. 8*. Synthesis and Structure of 2'-Amino-2-Oxo-1,2-Dihydro-6'H-Spiro-[Indole-3,4'-Pyrano[3,2-c][2,1]Benzothiazine]-3'-Carbonitrile 5',5'-Dioxides

Chemistry of Heterocyclic Compounds, 2014
2,2-Dioxides of 1-R-1H-2,1-benzothiazin-4(3H)-ones easily undergo a three-component condensation with N-substituted isatins and malononitrile in the presence of triethylamine giving 6'-R-1-R1-2'-amino-2-oxo-1,2-dihydro-6'H-spiro[indole-3,4'-pyrano[3,2-c][2,1]benzothiazine]-3'-carbonitrile 5',5'-dioxides in good yields. The reaction with 1-unsubstituted
I. V. Ukrainets, L. A. Petrushova, N. L. Bereznyakova, Liu Yangyang   +3 more
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ChemInform Abstract: A Convenient Synthesis of 3,4‐Dihydro‐2,2‐dioxide‐5‐hydroxy‐2,1‐ benzothiazine.

ChemInform, 1994
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
D. BLONDET, J.‐C. PASCAL
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Synthesis, characterization, monoamine oxidase inhibition, molecular docking and dynamic simulations of novel 2,1-benzothiazine-2,2-dioxide derivatives

Bioorganic Chemistry, 2018
In this research work, we report the synthesis and biological evaluation of two new series of 1-benzyl-4-(benzylidenehydrazono)-3,4-dihydro-1H-benzo[c] [1,2]thiazine 2,2-dioxides and 1-benzyl-4-((1-phenylethylidene)hydrazono)-3,4-dihydro-1H-benzo[c][1,2]thiazine 2,2-dioxides.
Shakeel, Ahmad, Sumera, Zaib, Saquib, Jalil, Muhammad, Shafiq, Matloob, Ahmad, Sadia, Sultan, Mazhar, Iqbal, Sana, Aslam, Jamshed, Iqbal   +8 more
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