Results 11 to 20 of about 16,660 (215)
3-Fluoro-N-(3-fluorobenzoyl)-N-(2-pyridyl)benzamide [PDF]
, 2009 The title compound, C19H12F2N2O2, a 2:1 product of the reaction of 3-fluorobenzoylchloride and 2-aminopyridine crystallizes with a disordered 3-fluorobenzene ring adopting two conformations [ratio of occupancies 0.959 (4):0.041 (4)].
Donnelly, Katie, Gallagher, John F.
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Entry point into new trimeric and tetrameric imide-based macrocyclic esters derived from isophthaloyl dichloride and methyl 6-aminonicotinate [PDF]
, 2012 The one-step reaction of isophthaloyl dichloride with the 2-aminopyridine derivative (methyl 6-aminonicotinate) yields (i) a trimer-based macrocycle (EsIO)3 and (ii) a tetramer-based macrocycle (EsIO)4 in modest isolated synthetic yields (total of 25 ...
Gallagher, John F., Mocilac, Pavle
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N-azinylpyridinium N-aminides: tandem reactions with alpha-halocarbonyl derivatives and analogs [PDF]
, 2000 Pyridinium-N-(2´-pyridyl)aminide was reacted with different α-halocarbonyl derivatives and related compounds. The method allows an easy preparation of several heterocyclic building blocks, all including the 2-aminopyridine moietyAuthor wish to thank C.I ...
Burgos García, Carolina +3 more
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Bis(2-aminopyridine-κN1)bis(benzoato-κO)cobalt(II)
Acta Crystallographica Section E, 2008 In the title compound, [Co(C7H5O2)2(C5H6N2)2], the CoII atom is hexacoordinated by four O atoms from two benzoate anions, and two N atoms from two 2-aminopyridine molecules, resulting in a distorted octahedral geometry.
Di-Chang Zhong +5 more
doaj +1 more source
A New Class of Small Molecule Inhibitor of BMP Signaling [PDF]
, 2013 Growth factor signaling pathways are tightly regulated by phosphorylation and include many important kinase targets of interest for drug discovery. Small molecule inhibitors of the bone morphogenetic protein (BMP) receptor kinase ALK2 (ACVR1) are needed ...
Bullock, AN +11 more
core +7 more sources
A Higher-Accuracy van der Waals Density Functional [PDF]
, 2010 We propose a second version of the van der Waals density functional (vdW-DF2) of Dion et al. [Phys. Rev. Lett. 92, 246401 (2004)], employing a more accurate semilocal exchange functional and the use of a large-N asymptote gradient correction in ...
Kong, Lingzhu +4 more
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Acta Crystallographica Section E, 2012 In the title complex, [Cu(C13H11N2O)Cl(C6H8N2)], the CuII atom adopts a distorted tetrahedral geometry being coordinated by the phenolic O atom and the azomethine N atom of the Schiff base ligand N-salicylidene 2-aminopyridine, and by the 2-aminopyridine
Bussa Bhagyaraju +2 more
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Bis(2-aminopyridine)dibenzoatocobalt(II)
Acta Crystallographica Section E Structure Reports Online, 2006 The title compound, [Co(C7H5O2)2(C5H6N2)2], contains CoII cations bonded to two bidentate benzoate ligands and two 2-aminopyridine ligands, resulting in highly distorted cis-CoN2O4 octahedra. The crystal structure is stabilized by N—H...O hydrogen bonds.
Wen-Zheng Ju +3 more
openaire +1 more source
Direct metalation of heteroaromatic esters and nitriles using a mixed lithium-cadmium base. Subsequent conversion to dipyridopyrimidinones. [PDF]
, 2010 International audienceAll pyridine nitriles and esters were metalated at the position next to the directing group using (TMP)(3)CdLi in tetrahydrofuran at room temperature.
Bentabed-Ababsa, Ghenia +7 more
core +3 more sources
Beilstein Journal of Organic Chemistry, 2009 Highly potent and selective inhibitors of neuronal nitric oxide synthase (nNOS) possessing a 2-aminopyridine group were recently designed and synthesized in our laboratory and were shown to have significant in vivo efficacy.
Graham R. Lawton +4 more
doaj +1 more source