Results 71 to 80 of about 16,660 (215)

Utility of N-2-pyridyl-3-oxobutanamide in heterocyclic synthesis: Synthesis of new dihydropyridine, fused pyridine, pyridopyridine, pyridazine and pyridopyrimidinethione derivatives [PDF]

, 2010
2-Aminopyridine was fused with ethyl acetoacetate without solvent for two hours to yield the  N-2-pyridyl–3-oxobutanamide 1. However, when the reaction time was increased to 5 hours a structure 3 was obtained.
Abdel Hafiz, I., Baker, Safaa, Hussein, A.   +2 more
core  

Targeting Hsp90 with cemdomespib reduces seizure burden and alters disease course in preclinical epilepsy models

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a chronic neurological disorder characterized by recurrent seizures and frequent cognitive and psychiatric comorbidities. Although current antiseizure medications provide symptomatic relief, they fail to prevent or modify epileptogenesis.
Yara Sheeni, Prince Kumar Singh, Sereen Sandouka, Taige Zhang, Alina Nemirovski, Aseel Saadi, Rhoda Olowe Taiwo, Matthew C. Walker, Tawfeeq Shekh‐Ahmad   +8 more
wiley   +1 more source

A pyridyl-substituted cyclodisilazane [(Apy)2(μ-SiMe)2] (ApyH2 = 2-aminopyridine)

IUCrData, 2017
The title compound, C14H20N4Si2 or [(Apy)2(μ-SiMe)2], systematic name 2-[2,2,4,4-tetramethyl-3-(pyridin-2-yl)-1,3,2,4-diazadisiletidin-1-yl]pyridine, was obtained as a side product from the reaction of 2-amino-pyridine with LiBun followed by the addition
Rui Li, Xin-E Duan, Wei Cao, Xue-Hong Wei   +3 more
doaj   +1 more source

A facile synthesis of N-H-and N-substituted acridine-1,8-diones under sonic condition [PDF]

, 2013
Synthesis of an assembly of structurally important N-H- and N-substituted acridine-1,8-diones by CAN (ceric ammonium nitrate) catalysed one-pot four-component reaction of electron-deficient and electron-rich aromatic aldehydes and aromatic amines or ...
Pasha, M.A., Sudha, S.
core   +3 more sources

Interictal and seizure‐onset scalp electroencephalographic patterns in malformations of cortical development

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development (MCDs) are a frequent cause of drug‐resistant epilepsy and a common indication for resective epilepsy surgery. As magnetic resonance imaging (MRI) lacks sensitivity for subtle MCDs, supplemental diagnostic tools are needed.
Lubna Shakhatreh, Liz Edenberg P. Quiles, Zhibin Chen, Ofer M. Genon, Saba Mohidat, Lyn Millist, Callum Hollis, Andrea Sundram, Piero Perucca, Terence J. O'Brien, Patrick Kwan   +10 more
wiley   +1 more source

Reimagining o‐Carborane‐Based Fluorophores: Charge‐Transfer from Boron Substituents Triggers Aggregation‐ and Crystallization‐Induced Emission

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
This work reports, for the first time, aggregation‐ or crystallization‐induced emission in boron‐substituted carboranes, which was driven by photoinduced charge‐transfer from fluorophore attached via boron vertices. The emission properties can be tuned by varying the substituents, expanding design strategies for luminescent materials.
Balázs Szathmári, Yanhong Gao, Dániel Buzsáki, Dániel Zámbó, Tamás Holczbauer, Antal Udvardy, Pál Szabó, Júlia Kertész, Dóra Hessz, Zsolt Kelemen   +9 more
wiley   +2 more sources

Structural Characteristics of Homoleptic Zinc Complexes Incorporating Asymmetric Aminopyridinates

Crystals
First examples of mononuclear homoleptic zinc aminopyridinates have been isolated by reacting the sterically bulky deprotonated 2-aminopyridine ligands, N-(2,6-diisopropylphenyl)-[6-(2,6-dimethylphenyl)-pyridine-2-yl]-amine (1) and N-(2,6 ...
Awal Noor, Sadaf Qayyum
doaj   +1 more source

Effects of ocean acidification on invertebrate settlement at volcanic CO2 vents [PDF]

, 2010
We present the first study of the effects of ocean acidification on settlement of benthic invertebrates and microfauna. Artificial collectors were placed for 1 month along pH gradients at CO2 vents off Ischia (Tyrrhenian Sea, Italy).
A Rittmann, B Michaelidis, BA Menge, BA Seibel, CD Keeling, CF Boudouresque, CF Boudouresque, D Iglesias-Rodriguez, D Tedesco, F Gazeau, F Porri, F. P. Patti, G Bellan, G Pulitzer Finali, G Pulitzer Finali, GC Cozzolino, GF Russo, GW Rouse, H Augier, H Kurihara, H Kurihara, H Kurihara, H Kurihara, HL Wood, HS Findlay, IB Kuffner, J Bijma, J Gobin, J Raven, J-P Gattuso, J. M. Hall-Spencer, JB Ries, JM Hall-Spencer, JP Barry, JT Houghton, K Caldeira, M Lorenti, M Sarà, M. C. Gambi, M. Cigliano, MA Green, MA Kendall, MB Scipione, MC Buia, MC Gambi, MC Gambi, MC Gambi, MI Lindinger, P Guidetti, PL deFur, PL Jokiel, R Rodolfo-Metalpa, R. Rodolfo-Metalpa, RA Feely, RE Zeebe, RP Ellis, S Dupont, S Martin, S Widdicombe, SL Dashfield, U Riebesell, U Riebesell, U Riebesell, U Riebesell   +63 more
core   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Treatment of the Rust Layer by Different Pyridine Derivatives and Its Effect on the Epoxy-Polyvinylbutyral Coating Directly Painted onto the Rust Mild Steel

International Journal of Electrochemical Science, 2017
In this work, 2-picolinicacid, 2-hydroxypyridine and 2-aminopyridine were used as rust converters to pre-process a metal surface. The results showed that the rust layers of A3 steel treated by pyridine derivatives are more compact and homogeneous than ...
Yinze Zuo, Zhaolei Li, Liang Chen, Yu Wang, Yanmin Gao   +4 more
doaj   +1 more source