Results 81 to 90 of about 16,660 (215)

Clinical, Genetic, and Imaging Characteristics of SCA27B: Insights from a Large Dutch Cohort

Movement Disorders, EarlyView.
Abstract Background Deep intronic GAA repeat expansions in intron 1 of the FGF14 gene were identified in 2023 as cause of late‐onset cerebellar ataxia. Since then, GAA‐FGF14‐related ataxia (SCA27B) has emerged as one of the most common genetic causes of late‐onset cerebellar ataxia.
Teije H. van Prooije, Maartje Pennings, Roderick P.P.W.M. Maas, Jeroen de Vries, Corien Verschuuren‐Bemelmans, Vincent Odekerken, Sirwan K.L. Darweesh, Mark Huisman, Mayke Oosterloo, Arthur Buijink, Jaron van de Wardt, Els Vanhoutte, Tsz Hang Wong, Lisette Koens, Eva de Boer, Judith van Gaalen, Martijn Beudel, Dareia S. Roos, Jorrit I. Hoff, Thimo Cornelissen, Meyke Schouten, Thatjana Gardeichik, Erica van der Looij, Christine Klein, Joanne Trinh, Erik‐Jan Kamsteeg, Bart van de Warrenburg   +26 more
wiley   +1 more source

Ti–Pd Alloys as Heterogeneous Catalysts for Hydrogen Autotransfer Reaction and Catalytic Improvement by Hydrogenation Effects [PDF]

, 2019
Ti−Pd alloys were investigated as heterogeneous catalysts for hydrogen autotransfer reactions. This is the first reported study of alloys as catalysts for hydrogen‐borrowing reactions using alcohols.
Kondo Ryota, Obora Yasushi, Suzuki Takeyuki, Takahashi Yuya, Takeshita Hiroyuki T, Utsunomiya Masayoshi, 大洞 康嗣, 竹下 博之, 近藤 亮太   +8 more
core   +1 more source

Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat α2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae [PDF]

, 2009
publishe
00397366, 1525, 1525, 2907, 2907, 2910, 2910, 2921, 2922, 2923, 2924, 2925, 2bfa7e53-ee2d-4af4-b215-37e9ff303ca8, 4d68973e-f6ff-4d7d-9439-c121d8831040, 50111802, 90238246, bd6a76a9-51e0-42ce-9e57-130004af2bc5, Kato, Koichi, Kato, Tatsuya, Nakajima, Makoto, Obara, Takakiyo, Ogata, Nakoto, Park, Enoch Y., Usui, Taichi, Yagi, Hirokazu   +24 more
core   +1 more source

Microwave‐Assisted Organic Syntheses in Deep Eutectic Solvents: A Win‐Win Association for Sustainable Chemistry

ChemistryOpen, EarlyView.
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye, Chefikou Salami, Emilie Thiery   +2 more
wiley   +1 more source

A hexahomotrioxacalix[3]arene-based ditopic receptor for alkylammonium ions controlled by Ag + ions 4 [PDF]

, 2018
A receptor cone-1 based on a hexahomotrioxacalix[3]arene bearing three pyridyl groups 21 was successfully synthesized, which has a C3-symmetric conformation and is capable of binding 22 alkylammonium and metal ions simultaneously in a cooperative fashion.
Elsegood, Mark, Elsegood, Mark R. J., Elsegood, Mark R.J., Georghiou, Paris, Georghiou, Paris E., Ikejiri, Yusuke, Jiang, Xue-Kai, Rahman, Shofiur, Redshaw, Carl, Teat, Simon, Teat, Simon J., Warwick, Thomas G, Wu, Chong, Yamato, Takehiko, Zeng, Xi   +14 more
core   +1 more source

A new revelation of Cd(II)-selenocyanate coordination polymer triggered by 2-aminopyridine: Synthesis, characterization, X-ray structure, integrated DFT, and biological relevance

Results in Chemistry
In this work, we synthesize, and X-ray characterize a new Cd(II)-selenocyanate coordination polymer (CP), [Cd(L)(NCSe)2] n, using the salts Cd(OAc)2·4H2O, 2-aminopyridine (2-ampy), and KSeCN in methanol.
Dhrubajyoti Majumdar, Jessica Elizabeth Philip, Sourav Roy, Bouzid Gassoumi, Sahbi Ayachi   +4 more
doaj   +1 more source

Imide-based trezimide and tennimide macrocycles. [PDF]

, 2013
Reaction of isophthaloyl dichloride (I) with 2-aminopyridine or 2-aminopyrimidine (O, 26O) provides a facile entry into a new class of imide-based ‘3+3’ macrocyclic trimer (IO)3, (26IO)3 (as trezimides), together with the known tetramer (IO)4, (26IO)4 ...
Gallagher, John F., Mocilac, Pavle
core   +2 more sources

Opening closed inward rectifier potassium channel doors

British Journal of Pharmacology, EarlyView.
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger, Fabian Kaiser, Marcel A. G. van der Heyden, Saïd Bendahhou   +3 more
wiley   +1 more source

Responsiveness to progesterone and potassium channel blockers 4-aminopyridine, tetraethylammonium and free Ca(2+) contentration in spermatozoa of patients with oligozoospermia/leucocytospermia

The Ukrainian Biochemical Journal, 2018
The present study was undertaken to evaluate [Ca2+]i signals that occur in human sperm cells exposed in vitro to three diverse compounds; progesterone, 4-aminopyridine (a highly effective inducer of hyperactivation in human sperm) and tetraethylammonium.
R. V. Fafula, G. V. Danylovych, A. S. Besedina, O. V. Melnyk, Z. D. Vorobets   +4 more
doaj   +1 more source

Remodelling of the natural product fumagillol employing a reaction discovery approach [PDF]

, 2011
In the search for new biologically active molecules, diversity-oriented synthetic strategies break through the limitation of traditional library synthesis by sampling new chemical space. Many natural products can be regarded as intriguing starting points
Balthaser, Bradley R., Beeler, Aaron B., Maloney, Meghan C., Porco, John A., Snyder, John K.   +4 more
core   +1 more source