Results 151 to 160 of about 97,768,097 (202)

2-Methoxyestradiol Nanocrystal Colloidal Dispersion [PDF]

, 2020
openaire   +1 more source

[Protective effects of 2-methoxyestradiol against hypoxic pulmonary hypertension in neonatal rats]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Xie O, Li SS, Luo Y, Wang L.
europepmc   +1 more source

Synthesis of New Analogs of 2-Methoxyestradiol

, 2023
openaire   +1 more source

2-Methoxyestradiol

openaire   +1 more source

Physiological and pharmacological effects of 2-methoxyestradiol

Acta Biochimica Polonica, 2015
openaire  

2-Methoxyestradiol Reduces Angiotensin II–Induced Hypertension and Renal Dysfunction in Ovariectomized Female and Intact Male Mice

Hypertension, 2017
Cytochrome P450 1B1 protects against angiotensin II (Ang II)–induced hypertension and associated cardiovascular changes in female mice, most likely via production of 2-methoxyestradiol.
Kafait U Malik, Shyamala Thirunavukkarasu, Luis Gabriel Navar   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

2-Methoxyestradiol—Biology and Mechanism of Action

Steroids, 2010
In the last decade the endogenous estradiol metabolite, 2-methoxyestradiol (2ME), has gained more and more interest due to its marked anticancerogenic properties and possible cardiovascular benefits, as shown in numerous animal and experimental investigations.
A O Mueck, A O Mueck, H Seeger
exaly   +3 more sources

Mechanism of Action of 2-Methoxyestradiol: New Developments

Drug Resistance Updates, 2003
2-Methoxyestradiol (2ME2) is an endogenous metabolite of estrogen that has both antiangiogenic and antitumor effects. In preclinical models, 2ME2 showed promising activity that led to its clinical development as an orally active, small-molecule inhibitor of angiogenesis.
Susan L Mooberry
exaly   +3 more sources

An Efficient, Practical Synthesis of 2-Methoxyestradiol

Steroids, 2010
An efficient and practical scheme to synthesize 2-methoxyestradiol has been developed. The key step was the copper-mediated methoxylation using ethyl acetate as a co-catalyst to introduce a methoxyl group. These synthetic procedures of four steps from 17beta-estradiol as starting material gave 2-methoxyestradiol with a 61% overall yield.
Minhang Xin, Qidong You, Hua Xiang
exaly   +3 more sources

Short Synthesis of 2-Methoxyestradiol and 2-Hydroxyestradiol

Steroids, 2003
The estrogen metabolite 2-methoxyestradiol was synthesized from estradiol bis-THP-ether which was 2-hydroxylated using the superbase LIDAKOR, trimethyl borate, and H(2)O(2), then methylated and deprotected to obtain 2-methoxyestradiol in three steps and 61% yield. 2-Hydroxyestradiol was obtained by deprotecting the 2-hydroxyestradiol bis-THP-ether from
Paula Kiuru, Kristiina Wähälä
exaly   +3 more sources