Results 51 to 60 of about 113,430,123 (286)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Whole-Person Impairment in Younger Retired NFL Players
Orthopaedic Journal of Sports Medicine, 2014 Background: Professional American football is a physically demanding, high-impact sport with an elevated risk of injury. Orthopaedic injuries may impose acute, short-term or cumulative consequences throughout a player’s lifetime.
Benjamin G. Domb MD +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Scientific ReportsCurrent medical and clinical ecosystem for dementia detection is inadequate for its early detection. Traditional cognitive assessments are introduced after cognitive impairment has begun to disrupt the real-world functioning of the person.
Yesoda Bhargava +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
فاعلية الألعاب اللغوية الإلکترونية في تنمية بعض مهارات الاستعداد القرائي لدى الأطفال المعاقين عقليا في مرحلة التهيئة بمدارس التربية الفکرية [PDF]
المجلة العلمية لکلية التربية - جامعة الوادى الجديد, 2017 هدف البحث الحالي إلى الکشف عن فاعلية الألعاب اللغوية الإلکترونية في تنمية بعض مهارات الاستعداد القرائي لدى الأطفال المعاقين عقليا- القابلين للتعلم- بمرحلة التهيئة بمدارس التربية الفکرية.
رقية محمود أحمد علي
doaj +1 more source
FEBS Open Bio, EarlyView.Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source
Multimodal Technologies and Interaction, 2018 This paper studies the use of eye tracking in a First-Person Shooter (FPS) game as a mechanism to: (1) control the attention of the player’s avatar according to the attention deployed by the player; and (2) guide the gameplay and game’s ...
João Antunes, Pedro Santana
doaj +1 more source
A nationwide student survey on biochemistry learning resources in Italy
FEBS Open Bio, EarlyView.We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti +4 more
wiley +1 more source
The Structure of the Set of Equilibria for Two Person Multicriteria Games [PDF]
In this paper the structure of the set of equilibria for two person multicriteria games is analysed. It turns out that the classical result for the set of equilibria for bimatrix games, that it is a finite union of polytopes, is only valid for ...
Borm, P.E.M. +2 more
core