Results 121 to 130 of about 42,888,361 (250)

One-pot two-step catalytic synthesis of 6-amino-2-pyridone-3,5-dicarbonitriles enabling anti-cancer bioactivity. [PDF]

RSC Adv, 2022
Nicely LG, Vala RM, Upadhyay DB, Nogales J, Chi C, Banerjee S, Patel HM.   +6 more
europepmc   +1 more source

Potential wool growth inhibitors. 2(1H)-Pyridone analogues of mimosine

, 1977
The syntheses of DL-α-amino-β-(5-hydroxy-6-oxo-1,6-dihydropyridin-2- yl)propionic acid (3) and DL-α-amino-β-(1-hydroxy-2-oxo-1,2- dihydropyridin-4-yl)propionic acid (4), 2(1H)-pyridone isomers of the naturally occurring depilatory amino acid L-mimosine ...
RLN Harris, T Teitei
core   +1 more source

Synthesis and Decarboxylation of Functionalized 2-Pyridone-3-carboxylic Acids and Evaluation of their Antimicrobial Activity and Molecular Docking. [PDF]

Iran J Pharm Res, 2021
Meghrazi Ahadi E, Azizian H, Fathi Vavsari V, Aliahmadi A, Shahsavari Z, Bijanzadeh HR, Balalaie S.   +6 more
europepmc   +1 more source

Evaluation of Self-Association Energies of 2-Pyridone Tautomers by Modified MNDO Methods

, 1990
P(論文)We have carried out the molecular orbital calculations supported by the modified MNDO methods (MNDO/H, Modified MNDO and Am1) to study the self-associations of formic acid, 2-pyridone and its tautomer, 2-pyridinol.
NOGUCHI, AKIHIRO, KONDO, SHINICHI, 25674, KUZUYA, MASAYUKI, 4538, 24503   +5 more
core  

Examining the safety of nicotinamide for skin cancer prevention: Review of adverse events, metabolism, and toxic dosages

JAAD Reviews
Nicotinamide (niacinamide) supplementation for non-melanoma skin cancer prevention has sparked controversy over the past decade due to its inconsistent evidence of chemoprevention and its recently challenged safety profile.
Katie R. Xu, BA, Micah Belzberg, MD, Allison T. Vidimos, MD, RPh   +2 more
doaj   +1 more source

N-methyl-2-pyridone-5-carboxamide: A novel uremic toxin?

, 2003
N-methyl-2-pyridone-5-carboxamide: A novel uremic toxin?BackgroundN-methyl-2-pyridone-5-carboxamide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation.
Szolkiewicz, Marek, Rutkowski, Przemyslaw, Swierczynski, Julian, Striley, Cindy, Rutkowski, Boleslaw, Smolenski, Ryszard T., Slominska, Ewa   +6 more
core   +1 more source

Late-stage functionalization of the 4-amino-2-pyridone chemotype using electrochemical and MCR approaches

We report the development and application of different strategies for the late-stage functionalization (LSF) of the biologically relevant 4-amino-2-pyridone chemotype.
Longo, Matteo, Radi, Marco, Giannessi, Lisa, Massera, Chiara   +3 more
core   +1 more source

Facile synthesis and cytotoxicity of substituted uracil-1'(N)-acetic acid and 4-pyridone-1'(N)-acetic acid esters of 20(S)-camptothecins

A series of novel substituted uracil-1'(N)-acetic acid esters (5–9) and 4-pyridone-1'(N)-acetic acid esters (10–11) of 20(S)-camptothecins (CPTs) have been synthesized by the acylation method.
Di-Zao Li (17955359), Zhao-Di Fu (17955362), Hong-Yan Liu (6290597), Xian-Dao Pan (17955365)   +3 more
core   +1 more source

N-Phenyl-2-Pyridone-Derived Endoperoxide Exhibiting Dual Activity by Suppressing both Lung Cancer and Idiopathic Pulmonary Fibrosis

Conventional light-driven photodynamic therapy (PDT) to generate toxic singlet oxygen are potential for cancer therapeutics but limited by the light penetrability and hypoxia tumor.
Ziang , Liu, Wen , Sun, Engin U. , Akkaya, Yu , Si, Xiao , Qian, Hao , Wu, Lei, Wang, Yun , Nie, Yue , Pan, Shengli , Zhang, Yanping , Li, Yuan , Qiao, Rensong , Sun   +12 more
core   +1 more source

Fluorescence Assay for the Determination of d-Panthenol Based on Novel Ring-Fused 2-Pyridone Derivative. [PDF]

Int J Mol Sci, 2020
Kasprzyk W, Świergosz T, Koper F.
europepmc   +1 more source