Nicotinamide (niacinamide) supplementation for non-melanoma skin cancer prevention has sparked controversy over the past decade due to its inconsistent evidence of chemoprevention and its recently challenged safety profile.
Katie R. Xu, BA +2 more
doaj +1 more source
Synthesis and Decarboxylation of Functionalized 2-Pyridone-3-carboxylic Acids and Evaluation of their Antimicrobial Activity and Molecular Docking. [PDF]
Meghrazi Ahadi E +6 more
europepmc +1 more source
The synthesis and structure of [Cu(2-Br-4-HOpy)2(2-Br-4-pyone)2](ClO4)2 • 2(2-Br-4-HOpy) • 2(2-Br-4-pyone) is reported [2-Br-4-HOpy = 2-bromo-4-hydroxypyridine; 2-Br-4-pyone = 2-bromo-(1H)4-pyridone]. The compound forms as a co-crystal in the triclinic P-
Jeffrey C. Monroe (5673371) +1 more
core +1 more source
2-pyridone ligands as a design platform for palladium-catalyzed C(sp2)-H functionalization reactions
2-Pyridone ligands have emerged as uniquely powerful promoters in transition-metal-catalyzed C–H functionalization, enabling transformations that are often inaccessible with conventional ligand classes.
Kotwal, Namrata +2 more
core +1 more source
Synthesis and structure-activity relationships of small-molecule 2-pyridone based CBX7 inhibitors. [PDF]
Wilson CR +5 more
europepmc +1 more source
Fluorescence Assay for the Determination of d-Panthenol Based on Novel Ring-Fused 2-Pyridone Derivative. [PDF]
Kasprzyk W, Świergosz T, Koper F.
europepmc +1 more source
The concise bioinspired total synthesis of the 4-hydroxy-2-pyridone family of natural products. [PDF]
Cruz RL, Sim KH, Chiok BN, Wuest WM.
europepmc +1 more source
Novel Synthesis and Antiviral Evaluation of New Benzothiazole-Bearing <i>N</i>-Sulfonamide 2-Pyridone Derivatives as USP7 Enzyme Inhibitors. [PDF]
Azzam RA, Elboshi HA, Elgemeie GH.
europepmc +1 more source
Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils. [PDF]
Adolfsson DE +10 more
europepmc +1 more source
Cordypyridones E-J: Antibiofilm 2-Pyridone Alkaloids from the Nematode Antagonistic Fungus <i>Laburnicola nematophila</i>. [PDF]
Wennrich JP +8 more
europepmc +1 more source

