Results 91 to 100 of about 42,888,361 (250)

Design, Synthesis and Anti-fibrosis Activity Study of N1-Substituted Phenylhydroquinolinone Derivatives

Molecules, 2012
Pirfenidone (5-methyl-1-phenyl-2(1H)-pyridone, PFD) is a small-molecule compound acting on multiple targets involved in pathological fibrogenesis and is effective to increase the survival of patients with fibrosis, such as idiopathic pulmonary fibrosis ...
Jun Chen, Lijian Tao, Qianbin Li, Bin Liu, Ling Wu, Gaoyun Hu   +5 more
doaj   +1 more source

Two New Megastigmane Sulphonoglucosides from

Natural Product Communications, 2009
Phytochemical study of the methanol extract of Mallotus anisopodus led to the isolation of two new megastigmane sulphonoglucosides, namely anisoposides A (1) and B (2), along with junipetrioloside A (3), bergenin (4), α-tocopherol, and N 1 -methyl-2 ...
Chau Van Minh, Nguyen Thi Kim Thanh, Tran Hong Quang, Nguyen Xuan Cuong, Nguyen Nghia Thin, Nguyen Hoai Nam, Yvan Vander Heyden, Joëlle Quetin-Leclercq, Phan Van Kiem   +8 more
doaj   +1 more source

Synthesis and Evaluation of Antitumor and Anti-Angiogenesis Activity of Pyrone- or Pyridone-Embedded Analogs of Cortistatin A

Marine Drugs
Simplified analogs of cortistatin A were synthesized and biologically evaluated to develop novel antitumor substances that target angiogenesis. To analyze the effect of substituents at positions corresponding to C-2 and/or C-4 of the A-ring, various ...
Yuri Fujimoto, Kanako Mizuno, Yuta Nakamura, Masayoshi Arai, Naoyuki Kotoku   +4 more
doaj   +1 more source

Synthesis, structure and solvatochromic properties of some novel 5-arylazo-6-hydroxy-4-phenyl-3-cyano-2-pyridone dyes

Chemistry Central Journal, 2012
Background A series of some novel arylazo pyridone dyes was synthesized from the corresponding diazonium salt and 6-hydroxy-4-phenyl-3-cyano-2-pyridone using a classical reaction for the synthesis of the azo compounds.
Alimmari Adel, Mijin Dušan, Vukićević Radovan, Božić Bojan, Valentić Nataša, Vitnik Vesna, Vitnik Željko, Ušćumlić Gordana   +7 more
doaj   +1 more source

Synthesis of 6-Nitroderivatives of Oxazolo[3,2-a]-pyridines and Their Reactions with Nucleophiles

Molecules, 2003
5-Nitro-2-pyridone can be selectively N-phenacylated, and the resulting phenacylpyridones I undergo cyclization to 6-nitrooxazolo[3,2-a]pyridinium salts II.
Eugene V. Babaev, Alexander A. Bush
doaj   +1 more source

The synthesis of 1-vinyl-2-pyridone

, 2012
Kim Dmitriy Gymnanovich – Dr. Sc. (Chemistry), Professor, Head of Organic Chemistry Subdepartment, Chemistry Department, South Ural State University. 76, Lenin avenue, Chelyabinsk, 454080.
Бердникова, Е. В., Berdnikova, E. V., Ким, Д. Г., Kim, D. G.   +3 more
core  

Solid-State Supramolecular Assembly of Salicylic Acid and 2-Pyridone, 3-Hydroxypyridine or 4-Pyridone

, 2017
Mechanochemical milling of equimolar mixtures of salicylic acid with three hydroxy derivatives of pyridine provided three new phases. With 2-hydroxypyridine, which is in fact present as 2-pyridone, a discrete cocrystal supramolecular assembly is formed ...
Halasz, Ivan, Barišić, Dajana, di Michiel, Marco, Krunoslav Užarević, Tireli, Martina, Tomislav Stolar, Užarević, Krunoslav, Marco di Michiel, Martina Tireli, Dajana Barišić, Ivan Halasz, Stolar, Tomislav, Stipe Lukin, Lukin, Stipe   +13 more
core   +1 more source

Unusual coordination behavior by a hydroxypyridine/pyridone ligand: Synthesis and structure of [(2-bromo-4-hydroxypyridine)₂(2-bromo-1(H)-4-pyridone)₂copper(II)] perchlorate • 2(2-bromo-4-hydroxypyridine) • 2(2-bromo-1(H)-4-pyridone)

, 2019
The synthesis and structure of [Cu(2-Br-4-HOpy)2(2-Br-4-pyone)2](ClO4)2 • 2(2-Br-4-HOpy) • 2(2-Br-4-pyone) is reported [2-Br-4-HOpy = 2-bromo-4-hydroxypyridine; 2-Br-4-pyone = 2-bromo-(1H)4-pyridone]. The compound forms as a co-crystal in the triclinic P-
Jeffrey C. Monroe (5673371), Mark M. Turnbull (1556680)   +1 more
core   +1 more source

Synthesis of 4,6-dimethyl-3-cyano-2-pyridone catalysed by amino acids

Zaštita Materijala, 2017
In this work the synthesis of 4,6-dimethyl-3-cyano-2-pyridone catalyzed by amino acids was studied. In the first part of the work, the optimization was carried out by varying the initial concentration of glycine, the molar ratio of the reactants ...
Nevena Ž. Prlainović, Nataša Ž. Šekuljica, Jelena M. Mirković, Dušan Ž. Mijin   +3 more
doaj   +1 more source

Pyridone-substituted Pyridyl imines as Functionalised ligands in Coordination Chemistry and Catalysis

, 2018
In this thesis, the synthesis and coordination chemistry of a series of novel NNN and NN proton responsive ligands are described. All the ligands and complexes have been characterized by a combination of multinuclear NMR spectroscopic techniques, mass ...
Mona Hanash A. Alhalafi (7716149)
core   +1 more source