Results 71 to 80 of about 4,834 (175)

Design, Synthesis, and Evaluation of Novel Δ²-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant. [PDF]

J Med Chem, 2023
Sarkar S, Mayer Bridwell AE, Good JAD, Wang ER, McKee SR, Valenta J, Harrison GA, Flentie KN, Henry FL, Wixe T, Demirel P, Vagolu SK, Chatagnon J, Machelart A, Brodin P, Tønjum T, Stallings CL, Almqvist F.   +17 more
europepmc   +1 more source

Design, Synthesis, and Mechanistic Study of 2-Pyridone-Bearing Phenylalanine Derivatives as Novel HIV Capsid Modulators. [PDF]

Molecules, 2022
Zhang X, Sun L, Xu S, Shao X, Li Z, Ding D, Jiang X, Zhao S, Cocklin S, Clercq E, Pannecouque C, Dick A, Liu X, Zhan P.   +13 more
europepmc   +1 more source

Synthesis of 5-(substituted phenylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones from ethyl 3-oxo-2-(substituted phenylazo)butanoates, Short communication [PDF]

Journal of the Serbian Chemical Society, 2011
A new procedure for the synthesis of known azo pyridone dyes is presented. A series of 5-(substituted arylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones were prepared from ethyl 3-oxo-2-(substituted phenylazo)butanoates and cyanoacetamide in acetone using ...
GORDANA UŠĆUMLIĆ, DUŠAN MIJIN, NATAŠA VALENTIĆ, JASMINA DOSTANIĆ   +3 more
doaj  

Pentaketides and 5-p-Hydroxyphenyl-2-pyridone Derivative from the Culture Extract of a Marine Sponge-Associated Fungus Hamigera avellanea KUFA0732. [PDF]

Mar Drugs, 2023
Klaram R, Dethoup T, Machado FP, Gales L, Kumla D, Hafez Ghoran S, Sousa E, Mistry S, Silva AMS, Kijjoa A.   +9 more
europepmc   +1 more source

A 2-pyridone amide inhibitor of transcriptional activity in Chlamydia trachomatis. [PDF]

Antimicrob Agents Chemother, 2023
Núñez-Otero C, Bahnan W, Vielfort K, Silver J, Singh P, Elbir H, Almqvist F, Bergström S, Gylfe Å.   +8 more
europepmc   +1 more source

Reaction of acyclic enaminones with methoxymethylene meldrum's acid: synthetic and structural implications

Journal of the Brazilian Chemical Society, 2003
The reaction of acyclic enaminones with methoxymethylene Meldrum's acid afforded N-adduct and/or C-adduct of enaminones in moderate to good yields. The regiochemistry of this reaction depends on the N-amino substituent of the enaminone. The C-adduct is a
Cunha Silvio, Silva Viviane C. da, Napolitano Hamilton B., Lariucci Carlito, Vencato Ivo   +4 more
doaj  

Two New 4-Hydroxy-2-pyridone Alkaloids with Antimicrobial and Cytotoxic Activities from Arthrinium sp. GZWMJZ-606 Endophytic with Houttuynia cordata Thunb. [PDF]

Molecules, 2023
Yin Y, Wang D, Wu D, He W, Zuo M, Zhu W, Xu Y, Wang L.   +7 more
europepmc   +1 more source

6-Halo-2-pyridone as an efficient organocatalyst for ester aminolysis. [PDF]

RSC Adv, 2021
Yamada T, Watanabe Y, Okamoto S.
europepmc   +1 more source

One-pot two-step catalytic synthesis of 6-amino-2-pyridone-3,5-dicarbonitriles enabling anti-cancer bioactivity. [PDF]

RSC Adv, 2022
Nicely LG, Vala RM, Upadhyay DB, Nogales J, Chi C, Banerjee S, Patel HM.   +6 more
europepmc   +1 more source

Synthesis and Decarboxylation of Functionalized 2-Pyridone-3-carboxylic Acids and Evaluation of their Antimicrobial Activity and Molecular Docking. [PDF]

Iran J Pharm Res, 2021
Meghrazi Ahadi E, Azizian H, Fathi Vavsari V, Aliahmadi A, Shahsavari Z, Bijanzadeh HR, Balalaie S.   +6 more
europepmc   +1 more source