Results 71 to 80 of about 42,888,361 (250)

An overview of synthesis and biological activities of 2-pyridone derivatives over the last decade

open access: yesDiscover Applied Sciences
2-Pyridone frameworks are a pervasive member of the N-heterocyclic family of both chemical and therapeutic interest. 2-Pyridones and their bridged analogues have wide occurrences in nature and the presence of both aromatic and amide groups in the ...
Lopamudra Das, Tista Sengupta
doaj   +1 more source

Synthesis of Some New Enaminoketones, Analogous of Milrinone, 4,Pyrones and Related 4-Pyridones [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 1996
Synthesis of 4-(N,N- dimethylamino)-3-aryl-3-butene-2-one, ethyl-5-aryl-4-oxo-4H-pyran-2-carboxylate, ethyl-5-aryl-4-pyridones-2-carboxylate and 5-aryl-3-cyano-5-methyl-2-pyridones (aryl=3-thienyl, 2-furyl) are described.
Aziz Shahrisa, Salar Hemmati
doaj  

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

open access: yesJournal of the Chinese Chemical Society, EarlyView.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Ultrafast Decay Dynamics of the 21ππ* Electronic State of N‑Methyl-2-pyridone

open access: yes
The ultrafast decay dynamics of N-methyl-2-pyridone upon excitation in the near-ultraviolet range of 261.5–227.9 nm is investigated using the femtosecond time-resolved photoelectron spectroscopy method.
Wenping Wu (121781)   +5 more
core   +1 more source

Comparative evaluation of noncanonical amino acids as site‐specific NMR probes for the complex of E. coli SSB with single‐stranded DNA without isotope labelling

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3601-3620, June 2026.
Genetic encoding of noncanonical amino acids (ncAA) enables their site‐specific installation in proteins. This work compares the nuclear magnetic resonance (NMR) performance of different ncAAs in a large protein−DNA complex (~ 100 kDa) without isotope labelling. The ncAAs deliver readily detectable NMR signals in the complex between E.
Sreelakshmi Mekkattu Tharayil   +7 more
wiley   +1 more source

Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman   +2 more
wiley   +1 more source

Biological evaluation of pyridone alkaloids on the endocannabinoid system [PDF]

open access: yes, 2017
Naturally occurring pyridone alkaloids as well as synthetic derivatives were previously shown to induce neurite outgrowth. However, the molecular basis for this biological effect remains poorly understood.
Marck, Nicolas   +16 more
core   +1 more source

Perchloratobis[1-(1,10-phenanthrolin-2-yl)-2-pyridone]zinc(II) perchlorate

open access: yesActa Crystallographica Section E, 2009
In the title mononuclear complex, [Zn(ClO4)(C17H11N3O)2]ClO4, the ZnII ion is coordinated in a distorted octahedral geometry. The dihedral angles between the pyridine rings and the mean planes of the 1,10-phenanthroline ring system in each of the 1-(1,10-
Qing Ru Zhao, Qi Sheng Liu, Qing Yun Liu
doaj   +1 more source

Surface‐Bound Superoxide Radical‐Mediated Photo‐Fenton Mineralization of Ciprofloxacin on Fe‐Sillenite Nanosheets

open access: yesAdvanced Science, Volume 13, Issue 29, 22 May 2026.
This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu   +9 more
wiley   +1 more source

Defect‐Regulated Electronic and Lattice Evolution in Na4VMn(PO4)3 Toward High‐Performance Sodium Storage

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT NASICON‐type Na4VMn(PO4)3 (NVMP) is a promising high‐capacity cathode for sodium‐ion batteries, yet its practical deployment is hindered by Mn3+‐driven lattice distortion, persistent oxygen vacancy defects, and sluggish Na+ transport, collectively resulting in accelerated performance degradation.
Deyi Zhang   +10 more
wiley   +1 more source

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