Results 111 to 120 of about 24,429,528 (155)

Optimization of 4-Amino-2-Pyridone Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9: Integrating Structure-Activity and Structure-Metabolism Relationships. [PDF]

ChemMedChem
Giannessi L, Lupo MG, Ugolotti M, Papotti B, Mattina B, Martina MG, Demurtas A, Padula C, Nicoli S, Crescenzio M, Ferri N, Zimetti F, Radi M.   +12 more
europepmc   +1 more source

Discovery of Substituted 5-(2-Hydroxybenzoyl)-2-Pyridone Analogues as Inhibitors of the Human Caf1/CNOT7 Ribonuclease. [PDF]

Molecules
Kaur I, Jadhav GP, Fischer PM, Winkler GS.   +3 more
europepmc   +1 more source

2-Pyridone Formation: An Efficient Method for the Solid-Phase Synthesis of Homodimers. [PDF]

Chemistry
Abboud SA, Kodadek T.
europepmc   +1 more source

Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat <i>Streptococcus pyogenes</i> skin and soft tissue infection. [PDF]

Sci Adv
Zou Z, Singh P, Pinkner JS, Obernuefemann CLP, Xu W, Nye TM, Dodson KW, Almqvist F, Hultgren SJ, Caparon MG.   +9 more
europepmc   +1 more source

Urinary Excretion of N¹-Methylnicotinamide and N¹-Methyl-2-Pyridone-5-Carboxamide and Mortality in Kidney Transplant Recipients. [PDF]

Nutrients, 2020
Deen CPJ, Veen AV, Gomes-Neto AW, Geleijnse JM, Berg KJBD, Heiner-Fokkema MR, Kema IP, Bakker SJL.   +7 more
europepmc   +1 more source

Imparting aromaticity to 2-pyridone derivatives by O-alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated apoptosis. [PDF]

J Enzyme Inhib Med Chem
Abdelaziz ME, El-Miligy MMM, Fahmy SM, Abu-Serie MM, Hazzaa AA, Mahran MA.   +5 more
europepmc   +1 more source

Iron-Catalyzed Reactions of 2-Pyridone Derivatives: 1,6-Addition and Formal Ring Opening/Cross Coupling. [PDF]

Chem Asian J, 2019
Huang L, Gu Y, Fürstner A.
europepmc   +1 more source

Urinary Excretion of N¹-methyl-2-pyridone-5-carboxamide and N¹-methylnicotinamide in Renal Transplant Recipients and Donors. [PDF]

J Clin Med, 2020
Deen CPJ, van der Veen A, Gomes-Neto AW, Geleijnse JM, Borgonjen-van den Berg KJ, Heiner-Fokkema MR, Kema IP, Bakker SJL.   +7 more
europepmc   +1 more source

Six Years (2012-2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2-Pyridone Compounds. [PDF]

Chem Rec, 2018
Fioravanti R, Stazi G, Zwergel C, Valente S, Mai A.   +4 more
europepmc   +1 more source

Structures, Photoresponse Properties, and Biological Activity of Dicyano-Substituted 4-Aryl-2-pyridone Derivatives. [PDF]

ACS Omega, 2019
Mandal T, Pathak S, Dey A, Islam MM, Seth SK, Masum AA, Ortega-Castro J, Ray PP, Frontera A, Mukhopadhyay S.   +9 more
europepmc   +1 more source