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Plasma metabolomics analysis in murine prerenal azotemia reveals changes in energy substrates, amino acid metabolism, and uremic toxins. [PDF]
Budnick I +9 more
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Transition Metal-Catalyzed Direct C(sp<sup>3</sup>)-H Functionalization Reactions of Aliphatic Carboxylic Acids. [PDF]
Mal S, van Gemmeren M.
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[N-(beta-phenylisopropyl)-2-pyridone].
A, Raczka, H, Bojarska-Dahlig
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Developments in the Chemistry of 2-Pyridone
Synthetic Communications, 2014Abstract The focus of our review is on the methods of synthesis and chemical reactivity of 2-pyridone and some derivatives as 2-chloro-3-nicotinonitrile in addition to the biological activity of the 2-pyridone moiety.
Wafaa S Hamama, Mostafa I Waly
exaly +3 more sources
Photoionization of 2-pyridone and 2-hydroxypyridine
We studied the photoionization of 2-pyridone and its tautomer, 2-hydroxypyridine by means of VUV synchrotron radiation coupled to a velocity map imaging electron/ion coincidence spectrometer. The photoionization efficiency (PIE) spectrum is composed of steps.
C. Poully, J. +10 more
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Charge Density Study of 2-Pyridone
The crystal structure of 2-pyridone has been redetermined from high-resolution X-ray data collected at 123 K. The molecule is in the lactam form. Bond lengths (corrected for rigid-body libration) and angles have been determined with s.u.'s of 0.001 Å and 0.1°, respectively.
H W, Yang, B M, Craven
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Synthesis and Biological activity of 2-Pyridone Derivatives: A Mini Review
Letters in Drug Design & Discovery, 2023The 2-pyridone nucleus is an important scaffold present in various compounds with diverse pharmacological activity. Among the reported 2-pyridone analogs, the majority of the compounds either have a substituted ring system or a fused ring system.
Krishan Kumar Verma +4 more
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Organic Letters, 2023
A Pd(II)-catalyzed straightforward oxidative naphthylation of unmasked 2-pyridone derivatives is described using a twofold internal alkyne as a coupling partner.
S. Bera +5 more
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A Pd(II)-catalyzed straightforward oxidative naphthylation of unmasked 2-pyridone derivatives is described using a twofold internal alkyne as a coupling partner.
S. Bera +5 more
semanticscholar +1 more source
Transition Metal‐Catalysed Direct C−H Bond Functionalizations of 2‐Pyridone Beyond C3‐Selectivity
Chemistry - an Asian Journal, 20202-Pyridone is a ubiquitous motif in natural products, drug molecules, ligands in catalysis and organic materials. There is a necessity of the direct step-economic methods for the construction of 2-pyridone based molecules.
Aniruddha Biswas +2 more
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Organic Letters, 2022
A rhodium(III)-catalyzed Satoh-Miura type oxidative annulation of N-aryl 2-pyridone derivatives is described using internal alkyne as a coupling partner. A weakly coordinating carbonyl group of the 2-pyridone ring is utilized for this transformation. The
S. Bera +3 more
semanticscholar +1 more source
A rhodium(III)-catalyzed Satoh-Miura type oxidative annulation of N-aryl 2-pyridone derivatives is described using internal alkyne as a coupling partner. A weakly coordinating carbonyl group of the 2-pyridone ring is utilized for this transformation. The
S. Bera +3 more
semanticscholar +1 more source

