Results 11 to 20 of about 22,728,623 (370)

CT Perfusion in Lacunar Stroke: A Systematic Review

Diagnostics, 2023
Background. The main theory underlying the use of perfusion imaging in acute ischemic stroke is the presence of a hypoperfused volume of the brain downstream of an occluded artery.
Marialuisa Zedde, Manuela Napoli, Ilaria Grisendi, Federica Assenza, Claudio Moratti, Franco Valzania, Rosario Pascarella   +6 more
doaj   +1 more source

The Venular Side of Cerebral Amyloid Angiopathy: Proof of Concept of a Neglected Issue

Biomedicines, 2023
Small vessel diseases (SVD) is an umbrella term including several entities affecting small arteries, arterioles, capillaries, and venules in the brain. One of the most relevant and prevalent SVDs is cerebral amyloid angiopathy (CAA), whose pathological ...
Marialuisa Zedde, Ilaria Grisendi, Federica Assenza, Gabriele Vandelli, Manuela Napoli, Claudio Moratti, Piergiorgio Lochner, David J. Seiffge, Fabrizio Piazza, Franco Valzania, Rosario Pascarella   +10 more
doaj   +1 more source

A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1884-1897, December 2022., 2022
Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song, Jiahui Xu, Wei Yuan, Ruixue Li, Hui Guo, Hanshu Gao, Cuiying Gu, Wenjing Feng, Yanan Ma, Haiqiang Guo, Zhaoqing Sun, Liqiang Zheng   +11 more
wiley   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1962-1973, December 2022., 2022
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino, Neus Falgàs, Isabel E. Allen, Mircea Balasa, Jaume Olives, José Contador, Magdalena Castellví, Jordi Juncà‐Parella, Núria Guillén, Sergi Borrego‐Écija, Bea Bosch, Guadalupe Fernández‐Villullas, Oscar Ramos‐Campoy, Anna Antonell, Lorena Rami, Raquel Sánchez‐Valle, Albert Lladó   +16 more
wiley   +1 more source

Early Hyperchloremia and Outcomes After Severe Traumatic Brain Injury: Analysis of Resuscitation Outcomes Consortium Hypertonic Saline Trial

Critical Care Explorations, 2022
BACKGROUND/OBJECTIVES:. To investigate the effect of the occurrence of early hyperchloremia on death or severe disability at 180 days in patients with severe traumatic brain injury (TBI). DESIGN:.
Adnan I. Qureshi, MD, Xiaoyu Ma, MS, Wei Huang, MA, Ravi S. Nunna, MD, Francisco Gomez, MD, Kunal Malhotra, MD, Niraj Arora, MD, Premkumar N. Chandrasekaran, MD, Farhan Siddiq, MD, Camilo R. Gomez, MD, Jose I. Suarez, MD   +10 more
doaj   +1 more source

Primary stroke prevention worldwide : translating evidence into action [PDF]

, 2022
Funding Information: The stroke services survey reported in this publication was partly supported by World Stroke Organization and Auckland University of Technology.
Abanto C., Abd-Allah F., Abera S.F., Addissie A., Adebayo O., Adeleye A.O., Adilbekov Y., Adilbekova B., Adoukonou T.A., Aguiar de Sousa D., Ajagbe T., Akhmetzhanova Z., Akinyemi R.O., Akpalu A., Alvarez Ahlgren J., Ameriso S., Andonova S., Awoniyi F.E., Bakhiet M., Barboza M., Basri H., Bath P., Beare R., Bello O., Bereczki D., Beretta S., Berkowitz A., Bernabe-Ortiz A., Bernhardt J., Berzina G., Bisharyan M., Bovet P., Brainin M., Budincevic H., Cadilhac D., Caso V., Chen C., Chin J., Chwojnicki K., Conforto A., Cruz V.T., D'Amelio M., Danielyan K., Davis S., Demarin V., Dempsey R., Dichgans M., Dokova K., Donnan G., Elkind M.S., Endres M., Feigin V.L., Fischer U., Gall S.L., Gankpe F., Gaye Saavedra A., Gil A., Giroud M., Gnedovskaya E., Hachinski V., Hafdi M., Hamadeh R., Hamzat T.K., Hankey G., Heldner M., Ibrahim E.A., Ibrahim N.M., Inoue M., Ishida M., Jee S., Jeng J.-S., Johnson W.D., Kalkonde Y., Kamenova S., Karaszewski B., Kelly P., Khan T., Kiechl S., Kondybayeva A., Korv J., Kravchenko M., Krishnamurthi R.V., Kruja J., Lakkhanaloet M., Langhorne P., Lavados P.M., Law Z.K., Lawal A., Lazo-Porras M., Lebedynets D., Lee T.-H., Leung T., Liebeskind D.S., Lindsay P., Lopez-Jaramillo P., Lotufo P.A., Machline-Carrion J., Mahal A., Makanjuola A., Markus H.S., Marquez-Romero J.M., Martins S., Medina M., Medukhanova S., Mehndiratta M.M., Merkin A., Mikulik R., Mirrakhimov E., Mohl S., Moscoso-Porras M., Muller-Stierlin A., Murphy S., Musa K.I., Nasreldein A., Nogueira R.G., Nolte C., Norrving B., Noubiap J.J., Novarro-Escudero N., Ogun Y., Oguntoye R.A., Oraby M.I., Orken D.N., Osundina M., Ovbiagele B., Owolabi M.O., Ozdemir A.O., Ozturk S., Paccot M., Pandian J., Phan H.T., Phan T.G., Phromjai J., Piradov P., Platz T., Potpara T., Ranta A., Rathore F., Richard E., Roth G., Sacco R.L., Sahathevan R., Santos Carquin I., Saposnik G., Sarfo F.S., Sharma M., Sheth K., Shobhana A., Suwanwela N., Svyato I., Sylaja P.N., Tao X., Thakur K.T., Thrift A.G., Toni D., Topcuoglu M.A., Torales J., Towfighi A., Truelsen T.C., Tsiskaridze A., Tulloch-Reid M., Useche N., Vanacker P., Vassilopoulou S., Vukorepa G., Vuletic V., Wahab K.W., Wang W., Wijeratne T., Wolfe C., Yaria J., Yifru Y.M., Yock-Corrales A., Yonemoto N., Yperzeele L., Zhang P.   +175 more
core   +2 more sources

Effects of intravenous furosemide plus small‐volume hypertonic saline solutions on markers of heart failure

ESC Heart Failure, 2021
Aims We sought to compare the effects of furosemide + hypertonic saline solution (HSS) treatment in patients with acute decompensated heart failure in comparison with furosemide alone and the response in a compensated state after an acute saline load ...
Antonino Tuttolomondo, Carlo Maida, Alessandra Casuccio, Domenico Di Raimondo, Roberto Fonte, Valerio Vassallo, Maria Grazia Puleo, Tiziana Di Chiara, Alba Mogavero, Alessandro Del Cuore, Mario Daidone, Antonella Ortello, Antonio Pinto   +12 more
doaj   +1 more source

THE COMBINATION OF SELECTED MANAGEMENT INSTRUMENTS TO ANALYZE QUALITY PROBLEMS [PDF]

Modern Management Review, 2021
The aim of the article is to propose the combination of selected quality management instruments in a sequential and repetitive manner and to identify the incompatibilities and causes of its occurrence.
Dominika SIWIEC, Stanislav VANDŽURA
doaj   +1 more source

G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D₂ Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation

Biomolecules, 2023
The D2 dopamine receptor (D2R) signals through both G proteins and β-arrestins to regulate important physiological processes, such as movement, reward circuitry, emotion, and cognition.
Marta Sánchez-Soto, Noelia M. Boldizsar, Kayla A. Schardien, Nora S. Madaras, Blair K. A. Willette, Laura R. Inbody, Christopher Dasaro, Amy E. Moritz, Julia Drube, Raphael S. Haider, R. Benjamin Free, Carsten Hoffman, David R. Sibley   +12 more
doaj   +1 more source