Results 21 to 30 of about 900,332 (265)

Glaucocalyxin A alleviates inflammatory response in rats with traumatic fracture [PDF]

Jichu yixue yu linchuang
Objective To investigate whether glaucocalyxin A can reduce inflammatory response in rats with traumatic fracture. Methods The rats were randomly divided into control group, model group, low GLA (GLA-L), high GLA dose group (GLA-H) and GLA-H+YC-1 (HIF ...
JIANG Bowen, MA Rui, WANG Peng, QU Zhe, LI Aiqun
doaj   +1 more source

Cryptogenic stroke. Part 2: paradoxical embolism

Медицинский совет, 2021
Cryptogenic stroke (CS) is defined as a subtype of stroke associated with a heterogeneous group of pathogenetic mechanisms that remained undetermined in the course of advanced diagnostic research.
A. A. Kulesh, D. A. Demin, A. V. Belopasova, S. A. Mekhryakov, O. I. Vinogradov, L. I. Syromyatnikova, A. A. Ziankou   +6 more
doaj   +1 more source

Virtual Development of a Single-Cylinder Hydrogen Opposed Piston Engine

Energies
A significant challenge in utilizing hydrogen in conventional internal combustion engines is achieving a balance between NOx emissions and brake power output.
Enrico Mattarelli, Stefano Caprioli, Tommaso Savioli, Antonello Volza, Claudiu Marcu Di Gaetano Iftene, Carlo Alberto Rinaldini   +5 more
doaj   +1 more source

Outcome of multimodal MRI-guided intravenous thrombolysis in patients with stroke with unknown time of onset

Stroke and Vascular Neurology, 2019
Objective Intravenous tissue plasminogen activator (tPA) is the standard therapy for patients with acute ischaemic stroke (AIS) within 4.5 hours of onset. Recent trials have expanded the endovascular treatment window to 24 hours.
Yue Wang, Wei Liu, Jie Zhao, Hongmei Zhao, Runtao Li, Jiangtao Li, Chang Liu, Juan Lv, Yanan Li, Dongpu Ma, Huaihai Hao, Xinguang Xiao, Junzhong Liu, Yongfeng Yin, Rongli Liu, Qiaoyan Yu, Yingjie Wei, Pengyan Li, Runqing Wang   +18 more
doaj   +1 more source

Factors for recurrent stroke among Asian patients with non-valvular atrial fibrillation under non-vitamin K antagonist oral anticoagulant therapy

Journal of the Formosan Medical Association, 2020
Background/purpose: Atrial fibrillation (AF) patients with a history of ischemic stroke or transient ischemic attack (TIA) carry excessive risk of recurrent stroke. Real-world data for the Asian population is scarce.
Shin-Yi Lin, Sung-Chun Tang, Li-Kai Tsai, Shin-Joe Yeh, Chih-Fen Huang, Jiann-Shing Jeng   +5 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The Role of Olive Oil in Cardiometabolic Risk

Metabolites
Olive oil, the primary fat source in the Mediterranean diet (MedDiet), is rich in monounsaturated fatty acids (MUFA), especially oleic acid, which constitutes 70–80% of its composition.
Andrea Salvo, Antonino Tuttolomondo
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

T cells modulate the microglial response to brain ischemia

eLife, 2022
Neuroinflammation after stroke is characterized by the activation of resident microglia and the invasion of circulating leukocytes into the brain. Although lymphocytes infiltrate the brain in small number, they have been consistently demonstrated to be ...
Corinne Benakis, Alba Simats, Sophie Tritschler, Steffanie Heindl, Simon Besson-Girard, Gemma Llovera, Kelsey Pinkham, Anna Kolz, Alessio Ricci, Fabian J Theis, Stefan Bittner, Özgün Gökce, Anneli Peters, Arthur Liesz   +13 more
doaj   +1 more source