Results 31 to 40 of about 900,332 (265)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
CFD Analysis of 2-Stroke Engines
Energy Procedia, 2015 Abstract1d and 3d CFD simulation is a standard engineering practice on 4-stroke engines. However, the application to the 2-Stroke cycle is not so trivial, in particular the transition from detailed CFD-3d analyses to simplified 1d engine simulations. A first critical issue is the correlation between the instantaneous cylinder gas composition and the ...
openaire +2 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
A New Design Concept for 2-Stroke Aircraft Diesel Engines
Energy Procedia, 2014 AbstractHigh power density, low weight, compact dimensions, high efficiency as well as reliability are the key factors in designing and dimensioning piston engines for General Aviation and Unmanned Aerial Vehicle (UAV) power plants. Despite of new available technologies, conventional solutions are still struggling to fulfill simultaneously all those ...
CANTORE, Giuseppe +2 more
openaire +2 more sources
Stroke and Vascular NeurologyBackground Atrial cardiomyopathy (AC) is an emerging concept explaining the pathophysiology of cardioembolic strokes in absence of atrial fibrillation (AF).
Yannick Béjot +12 more
doaj +1 more source
Frontiers in Neurology, 2018 Background and purposeStroke has been scarcely studied in Latin America (LA). The Mexican Institute of Neurology Stroke Registry was established in 1990 as a prospective computer-based database to register data obtained from patients admitted with stroke.
Antonio Arauz +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Acute ischemic stroke mimicking subarachnoid hemorrhage after coronary angioplasty
Romanian Journal of Internal Medicine, 2017 Use of non-ionic contrast media (CM) in coronary arteriography has been reported to cause transient cortical blindness, confusion, amnesia and very rare focal deficits.
Piršić Ana +3 more
doaj +1 more source
Annals of Medicine, 2023 Introduction Beta-2-microglobulin (B2M), cystatin C and lipocalin-2 (LCN-2) are established renal biomarkers, yet their roles in stroke have not been fully evaluated. We aimed to investigate the relationship of B2M, cystatin C, and LCN-2 with stroke risk
Juanying Zhen +10 more
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source