Results 21 to 30 of about 2,488,041 (247)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Indice

open access: yesStudi di Storia Medioevale e di Diplomatica: Nuova Serie, 2018
Indice del diciottesimo numero della ...
SSMD 2000
doaj  

Should We ‘Eat a Rainbow’? An Umbrella Review of the Health Effects of Colorful Bioactive Pigments in Fruits and Vegetables

open access: yesMolecules, 2022
Health promotion campaigns have advocated for individuals to ‘eat a rainbow’ of fruits and vegetables (FV). However, the literature has only focused on individual color pigments or individual health outcomes. This umbrella review synthesized the evidence
Michelle Blumfield   +6 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Publish-and-Flourish: Using Blockchain Platform to Enable Cooperative Scholarly Communication

open access: yesPublications, 2019
Scholarly communication is today immersed in publish-or-perish culture that propels non-cooperative behavior in the sense of strategic games played by researchers.
Emilija Stojmenova Duh   +6 more
doaj   +1 more source

Comparison of Perioperative Electrophysiological Measurements and Postoperative Results in Cochlear Implantation with a Slim Straight Electrode

open access: yesApplied Sciences, 2023
This research aims to determine whether a neural response telemetry (NRT) threshold determines the success of surgery. Furthermore, we examined whether the patient’s age, the etiology of their hearing loss, the depth of the electrode insertion, and a ...
Tina Gabrovec   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Crisis de dependencia en la Zona Sur. Desarrollo agrario y migraciones internas en el cantón de Osa, 1973-2000, de Antoni Royo Aspa

open access: yesRevista de Historia, 2009
La historiografía costarricense no ha abordado aún suficientemente la problemática del desarrollo agrario regional. En este sentido, la obra de Antoni Royo representa un gran aporte para diversas ciencias y disciplinas. La formación del autor en diversos
Andrea Montero Mora
doaj  

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