Results 41 to 50 of about 19,214,587 (391)
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
European Journal of Histochemistry, 2009 One of the main problems in making a personal choice among the papers published in EJH during the last year is that they cover a broad variety of topics. This is obviously related to the subject matter of a journal of histochemistry such is EJH, which covers basic research, application to pathology, new techniques and so on.
openaire +4 more sources
Influence of silicone oil tamponade after vitrectomy on intraocular pressure [Tamponada silikonskim uljem i njezin utjecaj na vrijednosti intraokularnog tlaka] [PDF]
, 2013 The aim of this prospective study was to determine the possible influence of the silicone oil tamponade after vitrectomy on the early intraocular pressure (IOP) elevation, which is a major risk factor for developing secondary glaucoma in patients with ...
Barać, Josip +5 more
core
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Ministries Examined: Laity, Clergy, Women, and Bishops in a Time of Change [PDF]
, 1989 Reviewed Book: Reumann, John Henry Paul. Ministries Examined: Laity, Clergy, Women, and Bishops in a Time of Change.
Jacobson, J. Robert
core +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Brazilian Journal of Operations & Production Management, 2010 This study analyzes the Management Practices and Results constructs from several ISO 9001:2000 certified and non-certified organizations in the Brazilian leather-footwear chain in order to identify possible differences in performance between those and to
Marcelo Hoss Almeida +2 more
doaj
Representing Londinium: The Influence of Colonial and Post-Colonial Discourses
Theoretical Roman Archaeology Journal, 2001 None
Francis Grew
doaj +2 more sources
The other GMP: good manufacturing practice and its importance in the validation of constructed pharmaceutical facilities [PDF]
, 2005 The work reported is part of an ongoing PhD study prompted by the particular difficulties encountered when two very different quality cultures interact (in this case Pharmaceutical industry clients and Construction industry providers).
Edge, Jerry +2 more
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