Results 41 to 50 of about 2,488,041 (247)

‘Romanisation’ and the Body

open access: yesTheoretical Roman Archaeology Journal, 2001
None
Gilly Carr
doaj   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Studi Implementasi Iso 9000 : 2000 pada Perusahaan Konstruksi di Makassar

open access: yesJurnal Teknik Sipil, 2010
Abstrak. Pengelolaan mutu yang sistematik dapat mengurangi biaya kegagalan produk dan jasa. Oleh karena itu diperlukan standar untuk melakukan pekerjaan yang efisien dengan menciptakan konsistensi mutu.
Muhammad Sapri Pamulu   +1 more
doaj  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Os atletas do anno 2000

open access: yesRevista de Educação Física, 1933
[...]
Brunno Zauli
doaj  

Medicine, Culture and Military Identity

open access: yesTheoretical Roman Archaeology Journal, 2001
None
Patricia A. Barker
doaj   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

El voto económico en las elecciones de 1996 y 2000: una comparación

open access: yesRevista Española de Ciencia Política, 2013
El artículo comprueba la hipótesis del voto económico en las elecciones generales de1996 y 2000. Argumenta que es necesario reflexionar sobre la lógica de la teoría delvoto económico y traducirla en términos empíricos de una manera más sofisticada quela ...
Marta Fraile
doaj  

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