Results 41 to 50 of about 5,575,143 (306)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017); Venice (Italy); October 31-November 4, 2017; Session "Circulation, Macro- and Microcirculation"

Journal of Pediatric and Neonatal Individualized Medicine, 2017
Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017); Venice (Italy); October 31-November 4, 2017 58th ESPR Annual Meeting, 7th International Congress of UENPS, 3rd International Congress of EFCNI ORGANIZING ...
--- Various Authors
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Economic impact of Norfolk Island reform scenarios [PDF]

, 2015
Summary The Centre for International Economics has modelled the impact of the following reforms on the Norfolk Island economy: ■ Core Reform — at the core of the proposed reforms is inclusion of Norfolk Island in the mainland’s welfare and Medicare ...
The Centre for International Economics
core  

Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017); Venice (Italy); October 31-November 4, 2017; Session "Neurology and Follow-up"

Journal of Pediatric and Neonatal Individualized Medicine, 2017
Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017); Venice (Italy); October 31-November 4, 2017 58th ESPR Annual Meeting, 7th International Congress of UENPS, 3rd International Congress of EFCNI ORGANIZING ...
--- Various Authors
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Editorial IX Jornadas Argentinas de Robótica | JAR 2017

Tecnología y Ciencia, 2019
El objetivo de estas jornadas es ofrecer un ámbito de reunión para investigadores argentinos y de otros países cuyo interés y dedicación estén orientados a la robótica y temas relacionados.
IX Jornadas Argentinas de Robótica - JAR
doaj  

Amend the Mental Health Care Act 2017: A Survey of Indian psychiatrists (Part 2)

Indian Journal of Psychiatry
Background: Information about the experience of practicing psychiatrists with the use of the Mental Health Care Act (MHCA), 2017, India, after 5 years of its promulgation has not been available.
Savita Malhotra, Shruti Srivastava, K.P Jayaprakashan, Mahesh R. Gowda, Nidhi Sharma, Mohan R. Gopalan, Vidyadhar G. Watve, Imon Paul   +7 more
doaj   +1 more source

Slovenske bibliografije v letu 2017

Knjižnica, 2018
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Matjaž Hočevar
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source