Results 51 to 60 of about 5,575,143 (306)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Burden of Disease Study 2017. [PDF]

open access: yes, 2018
BACKGROUND: Although the burden of influenza is often discussed in the context of historical pandemics and the threat of future pandemics, every year a substantial burden of lower respiratory tract infections (LRTIs) and other respiratory conditions ...
GBD 2017 Influenza Collaborators
core   +1 more source

Desafiar a gravidade, escutar as matérias: FIMFA e FIMP 2017

open access: yesSinais de Cena, 2018
«E PUR SI MUOVE» – GRAVIDADE E SUSPENSÃO Festival de Marionetas e Formas Animadas (11 a 28 de Maio).
Catarina Firmo
doaj  

Togo 2017

open access: yes, 2018
The demand for political alternance, initiated by institutional and electoral reforms, constituted the major contentious issue between the government and the challengers of the Gnassingbé regime throughout the year. Civil society organizations and representatives of the Christian church supported the demands of the opposition.
openaire   +3 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

CICM 2017

open access: yes, 2017
This book constitutes the refereed proceedings of the 10th International Conference on Intelligent Computer Mathematics, CICM 2017, held in Edinburgh, Scotland, in July 2017.

core   +1 more source

Florida SouthWestern State College 2017 Holocaust Memorial Event Schedule Flyer

open access: yes, 2017
Florida SouthWestern State College Holocaust Memorial Event Schedule Flyer.
2017,
core  

Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017); Venice (Italy); October 31-November 4, 2017; Session "Neonatal Pulmonology, Neonatal Respiratory Support, Resuscitation"

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2017
Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017); Venice (Italy); October 31-November 4, 2017 58th ESPR Annual Meeting, 7th International Congress of UENPS, 3rd International Congress of EFCNI ORGANIZING ...
--- Various Authors
doaj   +1 more source

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