Results 91 to 100 of about 10,507,342 (334)

Annotated Bibliography: The Reference Desk: Grand Idea or Gone Down the River?

, 2018
This bibliography is from a panel presentation at the 2017 ACL Conference. The goal of this panel was to explore different rationales or sets of values that illustrated the continuation of the reference desk and reference service as essential to the ...
Jones, Alison, McCoy, Erin, Rice, Amy C., Walz, Jennifer L.   +3 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Opini Netizen Terhadap “KPU” dan “Bawaslu” Pada Media Sosial X Pasca Pemilu 2024 [PDF]

Alvaricky, Mohammad Farrel. 2024. NIM. 202010040311553. Opini Netizen Terhadap KPU dan Bawaslu Pada Media Sosial X (Studi Pada Unggahan Tanggal 27-28 Februari 2024). Skripsi, Prodi Ilmu Komunikasi, Universitas Muhammadiyah Malang.
Alvaricky, Mohammad Farrel
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The Dynamics of Processing Knowledge in Citizen Science Projects. Enhancing Participation in Public Citizen Science Formats

Citizen Science: Theory and Practice
Scientific practice has increasingly integrated participatory approaches, with citizen science (CS) serving as a prominent mode of engaging publics in knowledge production.
Eva L. Wyss, Jannik Saal, Andrea Rapp, Stefan Schmunk, Nadine Dietz, Lena Dunkelmann, Nina Korb, Anna Naunheim   +7 more
doaj   +1 more source

PENERAPAN MODEL PEMBELAJARAN PROBLEM BASED LEARNING BERBASIS NILAI IMTAQ UNTUK MENINGKATKAN HASIL BELAJAR BIOLOGI SISWA SUBKONSEP DAMPAK PENCEMARAN BAGI KEHIDUPAN KELAS VII MTS DARU’L HIKAM KOTA CIREBON [PDF]

, 2015
LUTHFIA JAHRA : Penelitian ini dilatarbelakangi oleh kondisi siswa MTs Daru’l Hikam Kota Cirebon, dimana dalam proses pembelajarannya membutuhkan suatu alternatif pembelajaran yang dapat memacu semangat setiap siswa untuk secara aktif ikut terlibat ...
LUTHFIA JAHRA,
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Suppress or Not to Suppress … CRAFT It: A Targeted Metabolomics Case Study Extracting Essential Biomarker Signals Directly from the Full ¹H NMR Spectra of Horse Serum Samples

Metabolites
Background: There are a few very specific inflammation biomarkers in blood, namely lipoprotein NMe+ signals of protein clusters (GlycA and GlycB) and a composite resonance of phospholipids (SPC).
James Chen, Ayelet Yablon, Christina Metaxas, Matheus Guedin, Joseph Hu, Kenith Conover, Merrill Simpson, Sarah L. Ralston, Krish Krishnamurthy, István Pelczer   +9 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Identification and pathogenicity of Fusarium species associated with wilting and crown rot in almond (Prunus dulcis)

Scientific Reports
Severe Fusarium wilt and crown root symptoms were observed in almond orchards in Portugal. The present study elucidates the etiology of the disease through molecular, phenotypic, and pathogenic characterization. Three Fusarium isolates from Portugal were
Ana López-Moral, Begoña Isabel Antón-Domínguez, María Lovera, Octavio Arquero, Antonio Trapero, Carlos Agustí-Brisach   +5 more
doaj   +1 more source