Results 71 to 80 of about 4,869,221 (316)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

KINETOPROPHYLAXIS OF OSTEOPOROSIS IN ELDERLY PEOPLE IN THE POST COVID PERIOD

Sport şi Societate
Globally, there is a noticeable demographic increase in the elderly population, an inevitable reality. The introduction of restrictionsduring the COVID-19 pandemic had profound effects on global health, both directly through the sequelae ...
Zavalişca Aurica, Zavalişca Aurica
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

REHABILITATION OF PHYSICAL DECONDITION SYNDROME POST –COVID19 TO SECOND AGE MEN WITH EXOGENOUS OBESITY

Sport şi Societate
The global rise in overweight and obesity has become a significant health issue, particularly highlighted during the COVID-19 pandemic.
Pogorlețchi Ala, Mihailov Natalia
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PSYCHO-EDUCATIONAL ASSISTANCE FOR STUDENTS WITH DISABILITIES FROM INCLUSIVE UNIVERSITY INSTITUTIONS

Sport şi Societate
In recent years, in the Republic of Moldova, there have been radical changes in the educational system, and one of them specifically aims at the access of young people with disabilities to university studies.
Racu Serghei, Cebotaru Nina
doaj   +1 more source

ICSI 2024

This two-volume set LNCS 14788 and 14789 constitutes the refereed post-conference proceedings of the 15th International Conference on Advances in Swarm Intelligence, ICSI 2024, held in Xining, China, during August 23–26, 2024.

core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Phenolic Content, Microbiological and Physicochemical Qualities, and In Vitro Biological Activities of Two Monofloral Kinds of Honey from Edough Peninsula, Annaba, Algeria

Polish Journal of Food and Nutrition Sciences
Since antiquity, honey has attracted interest across cultures for its nutritional and health-promoting values. Hence, this study aimed to evaluate the phenolic contents, physicochemical and microbiological qualities and biological activities of two ...
Lazhari Tichati, Tahar Tata, Chahrazed Benzaid, Hiba Daas, Mohcene Allem, Ghoulem Tiar, Zihad Bouslama   +6 more
doaj   +1 more source