Results 211 to 220 of about 75,592 (343)

Endothelial dysfunction in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: current knowledge and novel biomarkers. [PDF]

Front Endocrinol (Lausanne)
Hubska J, Roszkowska Z, Bobrowicz M, Iwaniuk S, Rak-Makowska B, Ambroziak U.   +5 more
europepmc   +1 more source

Clinical Outcome, Hormonal Status, Gonadotrope Axis, and Testicular Function in 219 Adult Men Born With Classic 21-Hydroxylase Deficiency. A French National Survey [PDF]

, 2015
Claire Bouvattier, Laure Esterle, Peggy Renoult-Pierre, Aude Brac de la Perrière, F. Illouz, V. Kerlan, V. Pascal-Vigneron, Delphine Drui, Sophie Christin-Maître, F. Galland, Thierry Brue, Yves Reznik, F. Schillo, D Pinsard, X. Piguel, G. Chabrier, Bénédicte Decoudier, Philippe Émy, Igor Tauveron, Marie-Laure Raffin-Sanson, Jérôme Bertherat, Jean‐Marc Kuhn, Philippe Caron, Maryse Cartigny, Olivier Chabre, Didier Dewailly, Yves Morel, Philippe Touraine, Véronique Tardy-Guidollet, Jacques Young   +29 more
openalex   +1 more source

Lifestyle implications of the paradox and management of oxidative stress in sperm

The Journal of Physiology, EarlyView.
Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané, Ruben J. Moreira, Annamaria Russo, Maria L. Pereira, Pedro F. Oliveira, Davide Barreca, Marco G. Alves   +6 more
wiley   +1 more source

ROC‐325 Attenuates Hypoxia‐Induced Pulmonary Hypertension Through Dual Inhibition of Autophagy and Hypoxia‐Inducible Factor 2α Signaling

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
In hypoxia‐induced pulmonary hypertension, endothelial HIF‐2α accumulation and autophagic activation drive vascular remodeling. We demonstrate that the novel lysosomal inhibitor ROC‐325 simultaneously attenuates this pathogenic autophagy and promotes HIF‐2α degradation.
Changlei Bao, Shuxin Liang, Dingyuan Liu, Xingting Wang, Dan Bai, Chuangjia Huang, Hanliang Sun, Zi Yang, Bitao Wu, Zixuan Chen, Jieyi Feng, Zinan Luo, Jintao Long, Jinsheng Zhu, June Bai, Li Zhang, Aiai Chu, Caojin Zhang, Haiyang Tang   +18 more
wiley   +1 more source

Simple Virilizing 21-Hydroxylase Deficiency [PDF]

, 2020
openaire   +1 more source

Reduced Frequency of Biological and Increased Frequency of Adopted Children in Males With 21‐Hydroxylase Deficiency: A Swedish Population‐Based National Cohort Study

Journal of Clinical Endocrinology and Metabolism, 2017
H. Falhammar, L. Frisén, Christina Norrby, C. Almqvist, A. Hirschberg, A. Nordenskjöld, A. Nordenström   +6 more
semanticscholar   +1 more source

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Treatment and Follow-up of Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency in Childhood and Adolescence [PDF]

J Clin Res Pediatr Endocrinol
Peltek Kendirci HN, Ünal E, Dündar İ, Buluş AD, Odabaşı Güneş S, Şıklar Z.   +5 more
europepmc   +1 more source

Timing of Glucocorticoid Treatment Dictates Glucocorticoid Receptor Actions Modulating the NLRP3‐Inflammasome Activation in Macrophages

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Utilizing a clinically relevant course of treatment, our study reveals that glucocorticoids protect against the late NLRP3 inflammasome activation regulating the IL‐1β secretion, the processing of GSDM‐D and pyroptosis following signal 2 stimulation. These potent anti‐inflammatory effects are mediated by the activation of GR signaling and the expansion
David Diaz‐Jimenez, Robert H. Oakley, Jackson A. Hoffman, Carl D. Bortner, Fred Lih, Jianying Li, Jason G. Williams, Erica Scappini, Kevin E. Gerrish, Stavros Garantziotis, Trevor K. Archer, John A. Cidlowski   +11 more
wiley   +1 more source

Evaluation of Sleep Health in Children With Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.

J Clin Endocrinol Metab
Golob L, Mercado-Munoz Y, Liu W, Singh A, Hodges JS, Siegel L, Morero H, Gao Z, Tipp A, Simon SL, Sarafoglou K.   +10 more
europepmc   +1 more source