Results 101 to 110 of about 2,009,621 (269)

Association of Matrix Metalloproteinase 2 (MMP2) Plasma Level with Response and Survival in Patients Treated with Bevacizumab for Recurrent High Grade Glioma

, 2012
Émeline Tabouret, Françoise Boudouresque, Maryline Barrié, M. Matta, Céline Boucard, Anderson Loundou, M. Ouafik, Olivier Chinot   +7 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Matrix metalloproteinases 2 and 9 in rabbits with doxorubicin-induced cardiomyopathy

Pesquisa Veterinária Brasileira
: Some studies have shown the role played by matrix metalloproteinases and their inhibitors in doxorubicin cardiotoxicity. In this study, we sought to investigate how plasma and myocardial MMP 2 and 9 perform in rabbits with doxorubicin-induced ...
Sheila S.S. Nogueira, Marlos G. Sousa, Fabio N. Gava, Fernando A. Rosa, Guilherme D. Melo, Gustavo Dittrich, Gisele F. Machado, Aparecido A. Camacho   +7 more
doaj   +1 more source

The Effect of Chronic Immunosuppressive Regimens Treatment on Aortal Media Morphology and the Balance between Matrix Metalloproteinases (mmp-2 and mmp-9) and Their Inhibitors in the Abdominal Aorta of Rats [PDF]

, 2022
Anna Surówka, Kamila Szumilas, Aleksandra Wilk, Kamila Misiakiewicz-Has, Kazimierz Ciechanowski, Karolina Kędzierska-Kapuza   +5 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

SPINID

Green Processing and Synthesis, 2014
van den Berg Jeoffrey
doaj   +1 more source

On-demand release of doxorubicin by biocompatible nanoparticles sensing the matrix metallo-proteinase 2 in 3D tumor spheroids

, 2016
Guarnieri Daniela, Marco Biondi, Marco Cantisani, Valentina Belli, Martina Profeta, Raiola Luca, Netti Paolo   +6 more
openalex   +1 more source

Beyond Born-Oppenheimer treatment for the construction of triple-sheeted accurate diabatic Hamiltonian matrix of F+H₂ system [PDF]

, 2017
Bijit Mukherjee, Saikat Mukherjee, K. R. Shamasundar, Satrajit Adhikari   +3 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source