The aim of the study was to assess the importance of the measurement of matrix metalloproteinase 2 (MMP-2)and tissue inhibitor of matrix metalloproteinases 2 (TIMP-2) in patients with colorectal cancer (CRC) in relation to clinicopathologicalfeatures of ...
Magdalena Groblewska +4 more
doaj
On the Ratio L12/L21 For n = 2 Eigenvalue Problems: An Empirical Constraint For The Calculation of Force Constants (Extended L Matrix Approximation) [PDF]
Achim Müller, Nithya Mohan, U. Heidborn
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Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Exact conditions for preservation of the partial indices of a perturbed triangular 2 × 2 matrix function. [PDF]
Adukov VM, Mishuris G, Rogosin SV.
europepmc +1 more source
Notizen: Matrixisolierungs- und Isotopensubstitutionstechnik: Germaniumisotopenaufspaltung der v3(F2)-Schwingung von GeCl4 und Chlorisotopenaufspaltung von GeClnCl4-n / Matrix Isolation and Isotopic Substitution Technique: Germanium Isotopic Splitting Pattern of the v3(F2) Mode of GeCl4 and Chlorine Isotopic Splitting Pattern of GeClnCl4-n [PDF]
F. Königer +2 more
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RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Perspectives on the 2 × 2 Matrix: Solving Semantically Distinct Problems Based on a Shared Structure of Binary Contingencies. [PDF]
Neth H +4 more
europepmc +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Hypergeometric functions of 2×2 matrix argument are expressible in terms of Appel’s functions 𝐹₄ [PDF]
Tom H. Koornwinder +1 more
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YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source

