Results 71 to 80 of about 4,042,033 (199)

An \~{O}$(n^2)$ Time Matrix Multiplication Algorithm

open access: yes, 2020
We show, for the input vectors $(a_0, a_1, ..., a_{n-1})$ and $(b_0, b_1, ..., b_{n-1})$, where $a_i$'s and $b_j$'s are real numbers, after \~{O}$(n)$ time preprocessing for each of them, the vector multiplication $(a_0, a_1, ..., a_{n-1})(b_0, b_1, ...,
Han, Yijie
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A Quantum Affine Algebra for the Deformed Hubbard Chain

open access: yes, 2012
The integrable structure of the one-dimensional Hubbard model is based on Shastry's R-matrix and the Yangian of a centrally extended sl(2|2) superalgebra.
Beisert, Niklas   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Light-Cone Quantization of the c=2 Matrix Model

open access: yes, 1992
We study the large $N$ limit of an interacting \td\ matrix field theory, whose perturbative expansion generates the sum over planar random graphs embedded in two dimensions.
Banks   +31 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Nonlocal Matrix Generalizations of N=2 Super Virasoro Algebra

open access: yes, 1994
We study the generalization of second Gelfand-Dickey bracket to the superdifferential operators with matrix-valued coefficients. The associated Miura transformation is derived.
Huang, Wen-Jui
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Improved matrix-model calculation of the N=2 prepotential

open access: yes, 2004
We present a matrix-model expression for the sum of instanton contributions to the prepotential of an N=2 supersymmetric U(N) gauge theory, with matter in various representations. This expression is derived by combining the renormalization-group approach
A. Klemm   +40 more
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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