Results 81 to 90 of about 140,285 (306)

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

5′-Oxospiro-(fluorene-9,4′-imidazolidine)-2′-thione

Molbank
The structure verification of 5′-oxospiro-(fluorene-9,4′-imidazolidine)-2′-thione by NMR is reported. Toward this aim, 2D NMR techniques including 1H-1H COSY, HMQC, and HMBC experiments were used to assist with the assignment of the 1H and 13C chemical ...
Dimitar Stoitsov, Marin Marinov, Plamen Penchev, Petya Marinova, Neyko Stoyanov   +4 more
doaj   +1 more source

Shedding light on reaction mechanisms : structure determination of reactive intermediates and investigation of protein structural dynamics using 2D-IR spectroscopy

, 2013
Detailed knowledge of reaction mechanisms is key to understanding chemical, biological, and biophysical processes. For many reasons, it is desirable to comprehend how a reaction proceeds and what influences the reaction rate and its products.
Meßmer, Andreas T.
core  

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Solution conformation of peptide PTSP in DMSO-d6 analyzed by 2D NMR(抑前胸腺肽溶液构象的2D NMR初步分析)

Zhejiang Daxue xuebao. Lixue ban, 2005
抑前胸腺肽PTSP是一种重要的新发现的昆虫神经肽，能够在体内和体外条件下抑制促前胸腺素PTTH对蜕皮激素合成的促进作用，实验材料PTSP以固相方法合成.用2D NMR技术来考察PTSP的DMSO-d6溶液，并记录COSY，NOESY和13C HMQC-COSY谱用于构象分析.利用2D COSY和NOESY归属了1H NMR谱的全部共振峰；再利用HMQC-COSY使全部αC和βC共振峰也得到了归属.分析得到肽链的1H和13C的化学位移和质子间的NOE，结果表明PTSP在DMSO ...
CHENXi(陈熙), PANYuan-jiang(潘远江), HUAYue-jin(华跃进)   +2 more
doaj   +1 more source

Integrated Visible Light and Oxidant Protection Through Multifunctional Sunscreens

Advanced Healthcare Materials, EarlyView.
High‐energy visible radiation (HEVR), although less energetic than UV light, penetrates deeper into the skin and contributes to photoaging, pigmentation disorders, and oxidative stress. The development of new HEVR‐targeted filters, therefore, represents not only a scientific challenge but also a pressing public health and cosmetic industry need.
Beatriz Peñín, Raúl Losantos, Ignacio Funes‐Ardoiz, Diego Sampedro   +3 more
wiley   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Mobile 2D NMR quantitative evaluation method and its application at shale oil wellsite: A case study of the second member of Funing Formation, Subei Basin

Youqicang pingjia yu kaifa
Porosity and oil saturation are critical parameters in shale oil reservoir evaluation, but current laboratory measurements face challenges. In contrast, using wellsite mobile two-dimensional nuclear magnetic resonance (2D NMR) measurements can minimize ...
ZOU YOULONG, LI JUN, LIU JILONG, GUO BAOXIN, WANG LIANG   +4 more
doaj  

Interpreting 2D-NMR spectra using Grad-CAM [PDF]

Research Ideas and Outcomes
It has been shown that it is possible to train a (simple) neural network to classify nuclear magnetic resonance spectra by a substructures either being part of the chemical structure measured or not.
Enriko Kroon, Ricardo Borges, Rômulo de Jesus, Stefan Kuhn   +3 more
doaj   +3 more sources

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source