Results 101 to 110 of about 1,187,120 (265)

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Quality control of traditional Chinese medicine Chelidonii herba based on 2D-Q-NMR

Heliyon
Chelidonii herba is a traditional Chinese medicinal herb with effects including antispasmodic, analgesic, antitussive, and bronchodilator properties. Alkaloids are the main bioactive ingredients in Chelidonii herba.
Huanbang Zhang, Mengjie Chen, Yang Xu, Kun Wang, Hua Li, Lixia Chen, Chao Huang   +6 more
doaj   +1 more source

Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]

, 2009
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Madan Rehani, Rakesh Sharma, Arun Agrawala   +2 more
core  

13C-direct detected NMR experiments for the sequential J-based resonance assignment of RNA oligonucleotides [PDF]

, 2010
We present here a set of 13C-direct detected NMR experiments to facilitate the resonance assignment of RNA oligonucleotides. Three experiments have been developed: (1) the (H)CC-TOCSY-experiment utilizing a virtual decoupling scheme to assign the ...
Helena Kovacs, Christian Richter, Anna Wacker, Buck, Janina, Kovacs, Helena, Wolfgang Bermel, Wacker, Anna, Harald Schwalbe, Bermel, Wolfgang, Boris Fürtig, Fürtig, Boris, Schwalbe, Harald (Prof. Dr.), Richter, Christian, Janina Buck   +13 more
core   +1 more source

Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing

Advanced Materials, EarlyView.
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long, Huanyu Zhou, Jaewan Ko, Hongwei Tan, Jaemin Lim, Yanfei Zhao, Daehan Kang, Eojin Yoon, Gyeong‐Tak Go, Somin Kim, Seung‐Woo Lee, Chan‐Yul Park, Hyojun Choi, Hyeran Kim, Hyung Joong Yun, Sung Hyuk Park, Kwan Sik Park, Jeong Woo Park, Mungeun Kim, Yong Soo Cho, Ho Won Jang, Wenqiang Yang, Min Hyuk Park, Wan Ki Bae, Sebastiaan van Dijken, Joona Bang, Tae‐Woo Lee   +26 more
wiley   +1 more source

Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation

BMC Bioinformatics, 2007
Background Classifying nuclear magnetic resonance (NMR) spectra is a crucial step in many metabolomics experiments. Since several multivariate classification techniques depend upon the variance of the data, it is important to first minimise any ...
Günther Ulrich L, Ludwig Christian, Parsons Helen M, Viant Mark R   +3 more
doaj   +1 more source

Structural rearrangements of membrane proteins probed by water-edited solid-state NMR spectroscopy [PDF]

, 2009
We show that water-edited solid-state NMR spectroscopy allows for probing global protein conformation and residue-specific solvent accessibility in a lipid bilayer environment.
Ader, C., NMR Spectroscopy, Baldus, M., Seidel, K., Schneider, R., Etzkorn, M., Becker, S., Sub NMR Spectroscopy, Dep Scheikunde   +8 more
core   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Comparative analysis of NMR chemical shift predictions for proteins in the solid phase [PDF]

, 2009
A comparative analysis of nuclear chemical shift predictions of proteins in the solid state by rapid algorithms trained on and verified with solution-state NMR assignments is presented.
Ader, C., NMR Spectroscopy, Baldus, M., Seidel, K., Schneider, R., Etzkorn, M., Sub NMR Spectroscopy, Dep Scheikunde   +7 more
core   +1 more source

Rapid prediction of multi-dimensional NMR data sets using FANDAS [PDF]

, 2018
Solid-state NMR (ssNMR) can provide structural information at the most detailed level and, at the same time, is applicable in highly heterogeneous and complex molecular environments.
Baldus, Marc, NMR Spectroscopy, Ghose, Ranajeet, Sub NMR Spectroscopy, Narasimhan, Siddarth, Weingarth, Markus, Mance, Deni, Bonvin, Alexandre M.J.J., de Agrela Pinto, Cecilia   +8 more
core   +1 more source