Results 11 to 20 of about 5,167,436 (292)
Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE): advances and perspectives [PDF]
BioTechniques, 2008 The recent trend in science is to assay as many biological molecules as possible within a single experiment. This trend is evident in proteomics where the aim is to characterize thousands of proteins within cells, tissues, and organisms.
Haleem J. Issaq, Timothy D. Veenstra
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Decoding 2D-PAGE complex maps: Relevance to proteomicsā
Journal of Chromatography B, 2006 This review describes two mathematical approaches useful for decoding the complex signal of 2D-PAGE maps of protein mixtures. These methods are helpful for interpreting the large amount of data of each 2D-PAGE map by extracting all the analytical information hidden therein by spot overlapping.
PIETROGRANDE, Maria Chiara +3 more
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Chemometric Tools for 2D-PAGE Data Analysis
, 2021 Two-Dimensional Polyacrylamide Gel Electrophoresis (2D-PAGE) provides two-dimensional maps where proteins appear separated according to their isoelectric point (pI) and molecular weight (MW). Usually these maps are very complex (i.e., hundreds or thousands of spots can be present in each map), and characterized by a low reproducibility, which hinders ...
Robotti E., Cala Elisa, Marengo E.
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A New Algorithm for the Simulation of SDS 2D-PAGE Datasets
, 2012 This chapter describes a new software for the generation of simulated realistic sodium dodecyl sulfate two-dimensional polyacrylamide gel electrophoresis (SDS 2D-PAGE) images. In order to choose the simulation strategy to provide realistic 2D-PAGE maps the statistical characteristics of such images were taken into account, such as the distributions of ...
MARENGO, Emilio, ROBOTTI, Elisa
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Region-based Statistical Analysis of 2D PAGE Images. [PDF]
Comput Stat Data Anal, 2011 A new comprehensive procedure for statistical analysis of two-dimensional polyacrylamide gel electrophoresis (2D PAGE) images is proposed, including protein region quantification, normalization and statistical analysis. Protein regions are defined by the master watershed map that is obtained from the mean gel. By working with these protein regions, the
Li F +2 more
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2D-PAGE as an effective method of RNA degradome analysis. [PDF]
Mol Biol Rep, 2012 The continuously growing interest in small regulatory RNA exploration is one of the important factors that have inspired the recent development of new high throughput techniques such as DNA microarrays or next generation sequencing. Each of these methods offers some significant advantages but at the same time each of them is expensive, laborious and ...
Nowacka M +6 more
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Investigation of the applicability of Zernike moments to the classification of SDS 2D-PAGE maps
Analytical and Bioanalytical Chemistry, 2011 The aim of this work is to investigate the performance of multivariate classification techniques like partial least squares-discriminant analysis (PLS-DA) and linear discriminant analysis (LDA) when using Zernike moments as global image descriptors, in the classification of sodium dodecyl sulphate (SDS) two-dimensional polyacrylamide gel ...
MARENGO, Emilio +5 more
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2DBase: 2D-PAGE database of Escherichia coli [PDF]
Biochemical and Biophysical Research Communications, 2007 We present a web-based integrated proteome database, termed 2DBase of Escherichia coli which was designed to store, compare, analyse, and retrieve various information obtained by 2D polyacrylamide gel electrophoresis and mass spectrometry. The main objectives of this database are (1) to provide the features for query and data-mining applications to ...
Vijayendran, Chandran +4 more
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Mapping and Identification of the Urine Proteome of Prostate Cancer Patients by 2D PAGE/MS. [PDF]
Int J Proteomics, 2014 Proteome analysis of the urine has shown that urine contains disease-specific information for a variety of urogenital system disorders, including prostate cancer (PCa). The aim of this study was to determine the protein components of urine from PCa patients.
Kiprijanovska S +6 more
europepmc +4 more sources
Digit ratio (2D:4D) and gender inequalities across nations [PDF]
, 2014 Gender inequality varies across nations, where such inequality is defined as the disproportionate representation of one sex over the other in desirable social, economic, and biological roles (typically male over female).
Manning, John +5 more
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