Results 21 to 30 of about 317 (127)

2H-Pyrrole und Pyrrole aus 3-Phenyl-2H-azirinen

CHIMIA, 1976
Vinyl-phosphonium salts [2] and phenyl-vinyl-sulfone or divinylsulfone react with benzonitril-methylides a (which are photochemically generated from 3-phenyl-2H-azirines 1 and 2) to give, via the nonisolated intermediates of type b, 2H-pyrrole 4 and the
Ulrich Widmer, Nikolas Gakis, Bruno Arnet, Heinz Heimgartner, Hans Schmid   +4 more
doaj   +1 more source

Enantiomerically Enriched Aziridine‐2‐carboxylates via Copper‐Catalyzed Reductive Kinetic Resolution of 2H‐Azirines

Angewandte Chemie, Volume 137, Issue 26, June 24, 2025.
Kinetic resolution by copper hydride catalyzed reduction of 2H‐azirines secured optically enriched N‐H aziridine‐2‐carboxylates with excellent diastereoselectivity (>20:1) and good enantioselectivity (up to 94% ee). DFT calculations and non‐covalent interaction analysis established the reaction pathway and revealed two key non‐covalent interactions ...
Yinuo Zheng, Elvis Wang Hei Ng, Antonio Rizzo, Pauline Chiu   +3 more
wiley   +2 more sources

Reaktionen von 3-Dimethylamino-2,2-dimethyl-2H-azirin mit aromatischen Carbonsäurehydraziden

CHIMIA, 1978
Reaction of 3-dimethylamino-2,2-dimethyl-2H-azirine (1) with salicylic acid hydrazide (2c) in acetonitrile at room temperature gives the amidrazone 3c as a primary product in 78% yield. Cyclization of 3c in methanol leads to the 1,2,5,6-tetrahydro-1,2,4-
Stanislav Chaloupka, Heinz Heimgartner
doaj   +1 more source

Insertion of Nitriles Into a Gold(III)/Carbene Bond: A Direct and Powerful Entry to Imino‐Substituted Carbenes

Angewandte Chemie, Volume 137, Issue 23, June 2, 2025.
Stable imino‐substituted Au(III) carbenes are easily and efficiently prepared by trapping the transient (N^C^C)Au←:CH(dmp)+ carbene with nitriles. The corresponding free species are readily generated and display dual carbene / nitrile‐ylide reactivities. The diazo decomposition, nitrile insertion, and carbene transfer can be combined in three‐component
Rui Wei, Nina Albouy, Sonia Mallet‐Ladeira, Karinne Miqueu, Didier Bourissou   +4 more
wiley   +2 more sources

Light-induced synthesis of 2H-azirines and its applications in organic chemistry

Journal of Saudi Chemical Society
2H-azirines have represented versatile building motifs in the domain of organic chemistry owing to their excellent reaction activity induced by the high strain of the three-membered ring species.
Shibo Lin, Yiwen Chu, Junfeng Deng, Fangqing Xie, Lifeng Zhao   +4 more
doaj   +1 more source

Domino reactions of 2H-azirines with acylketenes from furan-2,3-diones: Competition between the formation of ortho-fused and bridged heterocyclic systems

Beilstein Journal of Organic Chemistry, 2014
3-Aryl-2H-azirines react with acylketenes, generated by thermolysis of 5-arylfuran-2,3-diones, to give bridged 5,7-dioxa-1-azabicyclo[4.4.1]undeca-3,8-diene-2,10-diones and/or ortho-fused 6,6a,12,12a-tetrahydrobis[1,3]oxazino[3,2-a:3′,2′-d]pyrazine-4,10 ...
Alexander F. Khlebnikov, Mikhail S. Novikov, Viktoriia V. Pakalnis, Roman O. Iakovenko, Dmitry S. Yufit   +4 more
doaj   +1 more source

Recent Contributions of Organic Synthesis to Forensic Science

ChemPlusChem, Volume 91, Issue 2, February 2026.
Forensic science is a multidisciplinary field that plays a vital role in providing scientific evidence for criminal investigations. This review highlights advances and opportunities at the interface between organic synthesis and forensic science, with applications in drug identification, forensic toxicology, and latent fingerprint detection and ...
Gustavo dos Santos Martins, Mariana dos Santos Dupim, Rodrigo Garcia Agostinho, Fernanda Gadini Finelli   +3 more
wiley   +1 more source

Synthesis of trifluoromethylated 2H-azirines through Togni reagent-mediated trifluoromethylation followed by PhIO-mediated azirination

Beilstein Journal of Organic Chemistry, 2018
The reaction of enamine compounds with the Togni reagent in the presence of CuI afforded β-trifluoromethylated enamine intermediates, which were converted directly to biologically interesting trifluoromethylated 2H-azirines by an iodosobenzene (PhIO ...
Jiyun Sun, Xiaohua Zhen, Huaibin Ge, Guangtao Zhang, Xuechan An, Yunfei Du   +5 more
doaj   +1 more source

Manganese(I)‐Catalyzed Access to Enantioenriched Chiral Aziridine Phosphines

Angewandte Chemie, Volume 137, Issue 3, January 15, 2025.
A highly enantioselective hydrophosphination of 2H‐azirines is reported based on a newly discovered Mn(I) catalyst that plays an important role in both the reactivity and stereoselectivity of the process. Various valuable aziridine phosphines can now be accessed in high yields and enantiopurities.
Chuang Ni, Tizian‐Frank Ramspoth, Marta Castiñeira Reis, Syuzanna R. Harutyunyan   +3 more
wiley   +2 more sources

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

ChemistryOpen, Volume 14, Issue 7, July 2025.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas, Gobind Kumar, Sanjeev Dhawan, Talent Makhanya, Parvesh Singh   +4 more
wiley   +1 more source