Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester [PDF]
, 2000 Methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxoylate acts as an efficient alkylating agent for a variety of five-membered aromatic heterocycles. The aziridines derived from heterocycles that bear an alpha-carbonyl substituent react with TFA to give ...
M. José Alves +4 more
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Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate
Beilstein Journal of Organic Chemistry, 2020 The reactivity of α-azidochalcones has been explored for the preparation of highly substituted oxazoles via a 2H-azirine intermediate. The azidochalcones, when treated with potassium thiocyanate in the presence of potassium persulfate, lead to 2,4,5 ...
Mysore Bhyrappa Harisha +4 more
doaj +1 more source
Photochemische Cycloaddition von 3-Phenyl-2H-azirinen mit Ketenen
CHIMIA, 1972 Irradiation of 2,2-dimethyl-3-phenyl- (1c) and 2,3-diphenyl-2H-azirine (1d) in benzene solution in the presence of ketene (5) yields 2,2-dimethyl-4-phenyl- (6) and 2,4-diphenyl-5-methylen-3-oxazoline (7), respectively. Similar cycloadducts (9a to d) are
H. Heimgartner +6 more
doaj +1 more source
Synthetic Strategies to Access Fluorinated Azoles. [PDF]
European J Org ChemThis review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
El-Gaber MKA +4 more
europepmc +2 more sources
Optically active aziridine esters by nucleophilic addition of nitrogen heterocycles to a chiral 2H-azirine-2-carboxylic ester [PDF]
, 2003 Chiral enriched ethyl 3-methyl-2H-azirine-2-carboxylate acts as an efficient alkylating agent for a variety of five membered aromatic nitrogen heterocycles.Fundação para a Ciência e Tecnologia - POCTI/32723/QUI/2000 ...
Alves, M. José +2 more
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Design and Synthesis of Stereogenic-at-Iron Complexes with Multidentate Ligands and Application in Asymmetric Catalysis [PDF]
, 2023 Asymmetric catalysis is an indispensable tool of great importance for the economic and sustainable synthesis of non-racemic chiral molecules. In addition to organic compounds and biomolecules, chiral transition metal complexes represent a pivotal pillar ...
Steinlandt, Philipp Stefan
core +1 more source
Accurate ring strain energies of unsaturated three-membered heterocycles with one group 13–16 element [PDF]
, 2022 © 2022 The Authors. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Published Manuscript version of a Published Work that appeared in final form in Inorganic ...
Espinosa Ferao, Arturo +1 more
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Diels-alder cycloaddition of 2-azadienes to methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate in the synthesis of methyl 4-oxo-1,3-diazabicyclo[4.1.0]heptane-6-carboxylates [PDF]
, 2004 A number of fused 4-oxo-1,3-diazabicyclo[4.1.0]heptane-6-carboxylates, a new type of compound, have been obtained by Diels-Alder cycloaddition between nucleophilic 2-azadienes and an electrophilic 2H-azirine.
Alves, M. José +2 more
core +1 more source
A catalyst-controlled selective synthesis of pyridines and pyrroles [PDF]
, 2014 We have developed a dual reaction manifold that enables selective synthesis of both pyridines and pyrroles from common substrates ??-diazo oxime ethers.
Alvarez-Corral +55 more
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Beilstein Journal of Organic Chemistry, 2015 The reaction of α-azidochalcones with carboxylic acids has been investigated resulting in the formation of α-amido-1,3-diketones under microwave irradiation via in situ formation of 2H-azirine intermediates.
Kandasamy Rajaguru +4 more
doaj +1 more source