Enantiomerically Enriched Aziridine‐2‐carboxylates via Copper‐Catalyzed Reductive Kinetic Resolution of 2H‐Azirines [PDF]
Angewandte Chemie, Volume 137, Issue 26, June 24, 2025.Kinetic resolution by copper hydride catalyzed reduction of 2H‐azirines secured optically enriched N‐H aziridine‐2‐carboxylates with excellent diastereoselectivity (>20:1) and good enantioselectivity (up to 94% ee). DFT calculations and non‐covalent interaction analysis established the reaction pathway and revealed two key non‐covalent interactions ...
Yinuo Zheng +3 more
wiley +4 more sources
Stabile Zink-Komplexe von 3-Amino-2H-azirinen [PDF]
CHIMIA, 1978 3-Dimethylamino-2,2-dimethyl-2H-azirine (4a), which is known to react easily with Brönsted acids and electrophiles, forms a stable complex 5a with ZnBr2. In contrast to all other reactions of 4a, the three-membered ring in this complex is preserved. The
Kurt Dietliker +3 more
doaj +3 more sources
2-Oxo-4H-imidazolium-1-acetamidate, neue stabilisierte Dipole aus Aminoazirinen und NH-aciden Heterocyclen [PDF]
CHIMIA, 1985 3-Dimethylamino-2,2-dimethyl-2H-azirine (1) and 5-trifluoromethyl-1,3,4- oxadiazol-2(3H)-on (9) in 2-propanol react already at room temperature to give the dipolar compound 10 in reasonable yield (Scheme 4).
Roland Prewo +2 more
doaj +3 more sources
Bildung eines Azacyclols durch transanulare Ringkontraktion [PDF]
CHIMIA, 1988 Reaction of 3-dimethylamino-2,2-dimethyl-2H-azirine (1) with phthalimide (8) in polar solvents yields the (1:1)-adduct 2-dimethylamino-9b-hydroxy-3,3-dimethyl-5,9b-dihydro-3H-imidazo[2,1-a]isoindol-5-one (10).
Marlise Schläpfer-Dähler +4 more
doaj +3 more sources
Reaktionen von 3-Dimethylamino-2,2-dimethyl-2H-azirin mit aromatischen Carbonsäurehydraziden [PDF]
CHIMIA, 1978 Reaction of 3-dimethylamino-2,2-dimethyl-2H-azirine (1) with salicylic acid hydrazide (2c) in acetonitrile at room temperature gives the amidrazone 3c as a primary product in 78% yield. Cyclization of 3c in methanol leads to the 1,2,5,6-tetrahydro-1,2,4-
Stanislav Chaloupka, Heinz Heimgartner
doaj +3 more sources
Copper(II)-Catalyzed (3+2) Cycloaddition of 2H-Azirines to Six-Membered Cyclic Enols as a Route to Pyrrolo[3,2-c]quinolone, Chromeno[3,4-b]pyrrole, and Naphtho[1,8-ef]indole Scaffolds. [PDF]
Molecules, 2022 Sakharov PA +3 more
europepmc +3 more sources
Stereoselective cycloaddition of 1-glucosyl-1,3-butadienes with tert-butyl 2H-azirine-3-carboxylate, glyoxylates and imines [PDF]
, 2003 Glucosyl dienes 1 have been reacted with the achiral 2H-azirine 4 and with glyoxylates, forming fused structures of type 5 and disaccharide-like compounds 7 with good to excellent selectivity.
M. José Alves +3 more
openalex +4 more sources
Cycloaddition of methyl 2-(2,6-dichorophenyl)-2H-azirine-3-carboxylate to electron-rich 2-azadienes [PDF]
, 2003 Tert-Butyldimethylsililoxy-2-aza-1,3-butadienes react with 2H-azirine 3 leading to Diels-Alder cycloadducts in moderate yields. The reactions are endo- and regio- selective with the azirine being added by its less hindered face. There is only one product
M. José Alves +2 more
openalex +4 more sources
Crystal structure of 3-methylamino-2,2-diphenyl-2H-azirine, (HNCH3)C2N(C6H5)2 [PDF]
Zeitschrift für Kristallographie - New Crystal Structures, 2000 Peters K. +3 more
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Non-Aziridination Approaches to 3-Arylaziridine-2-carboxylic Acid Derivatives and 3-Aryl-(aziridin-2-yl)ketones. [PDF]
Int J Mol Sci, 2022 Funding Information: APC was covered by Riga Stradins University, Riga, Latvia. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Highly functionalized aziridines, including compounds with aromatic moieties, are attractive ...
Strumfs B +4 more
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