Selective Synthesis of 3‑(1H‑Tetrazol-5-yl)-indoles from 2H‑Azirines and Arynes [PDF]
ACS OmegaA new selective synthetic approach to indole derivatives bearing a tetrazole moiety has been developed. Arynes, generated in situ from o-(trimethylsilyl)aryl triflates and KF, reacted smoothly with 2-(2-benzyl-2H-tetrazol-5-yl)-2H-azirines to give 3-(2 ...
Carla Grosso +6 more
doaj +3 more sources
Reactivity of 2-halo-2H-azirines. Part 3: Dehalogenation of 2-halo-2H-azirine-2-carboxylates [PDF]
Tetrahedron, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Pinho e Melo, Teresa M. V. D. +2 more
openaire +4 more sources
2H-Azirines as electrophiles [PDF]
, 2011 2H-Azirines have shown an unusual potential to synthesise aziridines and other types of compounds. Many functionalized aziridines can be produced by addition of O-, S-,N-, C-nucleophiles and hydride to 2H-azirines. This review is designed to give an overview of the reactivity of 2H-azirines as electrophiles along the years and their usefulness in the ...
Alves, M. José, Costa, Flora Teixeira e
core +4 more sources
Light-Induced Synthesis of 2H-Azirines and Its Applications in Organic Chemistry
Journal of Saudi Chemical Society2H-azirines have represented versatile building motifs in the domain of organic chemistry owing to their excellent reaction activity induced by the high strain of the three-membered ring species.
Yiwen Chu, Junfeng Deng, Lifeng Zhao
exaly +3 more sources
Cobalt catalyst with exclusive metal-centered chirality for asymmetric photocatalysis [PDF]
Nature CommunicationsFor decades, progress in chiral transition metal catalysis has been closely linked to the design of tailor-made chiral ligands. Recently, an alternative to this conventional paradigm has emerged in which the overall chirality of the catalysts arises ...
Su-Yang Yao +7 more
doaj +2 more sources
Substituent Effects Govern the Efficiency of Isoxazole Photoisomerization to Carbonyl‑2H‑Azirines [PDF]
ACS Organic & Inorganic AuKyra E. Jackson +3 more
doaj +2 more sources
A Novel Class of "Super-Strained" Spiro Heterocycles: Gateway to 1-Azaspiro[3.3]heptane Derivatives, and Biological Validation. [PDF]
Angew Chem Int Ed EnglA new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Natho P +9 more
europepmc +3 more sources
Lewis Acid Mediated Alkylation and Diels-Alder Reactions of 2H-Azirines [Elektronisk resurs]
, 2002 This thesis describes the use of 2H-azirines as reactivesubstrates in Lewis acid catalysed nucleophilic additions andin the Diels-Alder reaction.A number of carbon nucleophiles have been added to aseries of 2H-azirines in the presence and absence ofBF3 ...
Risberg, Erik,
core +7 more sources
Synthesis of Δ1‑Pyrrolines via Formal (3 + 2)-Cycloaddition of 2H‑Azirines with Enones Promoted by Visible Light under Continuous Flow [PDF]
ACS OmegaLorena S. R. Martelli +4 more
doaj +2 more sources
Synthesis and Application of Bioactive N-Functionalized Aziridines. [PDF]
Angew Chem Int Ed EnglThis review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Tan H +4 more
europepmc +3 more sources