Accurate ring strain energies of unsaturated three-membered heterocycles with one group 13–16 element [PDF]
, 2022 © 2022 The Authors. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Published Manuscript version of a Published Work that appeared in final form in Inorganic ...
Espinosa Ferao, Arturo +1 more
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I. The Synthesis, Absolute Configuration, and Stereochemistry of Thermal Decomposition of (+)-3R,5R- and (+)-3R,5S-3-Ethyl-5-Methyl-1-Pyrazoline. II. Mechanistic Investigations of the Thermal Decompositions of 2H-Azirines [PDF]
, 1976 I. (+)-3R,5R- and (+)-3R,5S-3-ethyl-5-methyl-1-pyrazolines (34T and 34C, respectively) have been prepared in optically active form. Their stereochemistries have been determined by correlation with (-)-R-3-hexanol and (-)-R-2-bromohexane.
Wendling, Larry Allan
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Diels–alder reactions of alkyl 2H-azirine-3-carboxylates with furans [PDF]
, 2001 Methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate 1 and furan give the aziridine 2 by a Diels–Alder cycloaddition reaction. The hydrolysis of compound 2 leads to a dihydrofuranol 11 by cleavage of a C–N bond.
Alves, M. José +5 more
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Gold(I)-catalyzed synthesis of 3-sulfenyl pyrroles and indoles by a regioselective annulation of alkynyl thioethers [PDF]
, 2021 [Image: see text] The combination of nucleophilic nitrenoids and π-acid catalysis has emerged as a powerful tool in heterocycle synthesis. Accessing more varied heterocycle-substitution patterns by maintaining the same reaction pathways across different ...
Davies, Paul +3 more
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Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations
Angewandte Chemie International Edition, EarlyView.The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach +4 more
wiley +1 more source
Research Experience for Undergraduates Program, 2010 [PDF]
, 2010 Supported by the National Science ...
University of Arkansas, Fayetteville. Dept. of Chemistry and Biochemistry
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Synthesis and reactivity of 2-halo-2H-azirines towards nucleophiles [PDF]
, 1997 Nucleophilic substitution reactions of 2-halo-2H-azirine with potassium phthalimide and aniline allowed the preparation of new substituted 2H-azirines.
Pinho e Melo, Teresa M. V. D. +2 more
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Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester [PDF]
, 2000 Methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxoylate acts as an efficient alkylating agent for a variety of five-membered aromatic heterocycles. The aziridines derived from heterocycles that bear an alpha-carbonyl substituent react with TFA to give ...
Alves, Maria José Chão +4 more
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Synthesis and Antiproliferative Activity of Phosphorus Substituted 4-Cyanooxazolines, 2-Aminocyanooxazolines, 2-Iminocyanooxazolidines and 2-Aminocyanothiazolines by Rearrangement of Cyanoaziridines [PDF]
, 2021 Several phosphorus-substituted N-acylated cyanoaziridines 2 and N-carbamoylated cyanoziridines 5 were prepared in good to high yields. N-Acylated cyanoaziridines 2 were used, after ring expansion, in an efficient synthesis of oxazoline derivative 3a and ...
Carramiñana Jiménez, Víctor +3 more
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Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application
European Journal of Organic Chemistry, EarlyView.Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
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