Results 61 to 70 of about 79,082 (160)

Copper-Catalyzed Highly Enantioselective Addition of a Silicon Nucleophile to 3-Substituted 2H-Azirines Using an Si-B Reagent. [PDF]

Angew Chem Int Ed Engl, 2023
Zhao ZY, Cui M, Irran E, Oestreich M.
europepmc   +1 more source

Highly Enantioselective Reductions of 2H-Azirines

Herein, we present the first highly enantioselective reduction of mono- and tri- substituted 2H-azirines mediated by a chiral copper-hydride complex. The reaction tolerates both alkylated and arylated 2H-azirines to afford free N-H aziridines in excellent yield (up to 96%) and enantioselectivity (up to 96% ee). A key finding was the stark difference in
Yinuo Zheng, Elvis Wang Hei Ng, Yongjie Shi, Antonio Rizzo, Pauline Chiu   +4 more
openaire   +1 more source

Molybdenum hexacarbonyl-induced reactions of 3-aryl-2h-azirines and acetylenes

, 1979
In the presence of molybdenum hexacarbonyl, 3-phenyl-2H-azirines and acetylene carboxylic acid esters react via the unusual splitting of the C,N-double bond to give 2H-pyrroles or ...
Inada, Akira, Heinz Heimgartner, Hans Schmid, Heimgartner, Heinz, Schmid, Hans, Akira Inada   +5 more
core   +1 more source

Asymmetric Syntheses of Aziridine-2-carboxylates via Reductive Kinetic Resolution of 2H-Azirines [PDF]

Enantioenriched aziridine-2-carboxylates are valuable organic compounds thanks to their versatility as chiral building blocks. Several syntheses of bioactive molecules employ aziridine-2-carboxylates as a crucial synthetic intermediate, e.g.
Antonio, Rizzo, Yinuo, Zheng, Pauline, Chiu   +2 more
core   +2 more sources

Transition-metal-free synthesis of substituted pyridines via ring expansion of 2-allyl-2H-azirines

, 2014
A new strategy to open the 2-allyl-2H-azirines by 1,8-diazabicyclo[5.4.0] undec-7-ene (DBU) promotion in metal-free conditions affording 1-azatrienes that in situ electrocyclize to the pyridines in good to excellent yields is reported.
Loh, Teck-Peng, Teck-Peng Loh, Cheol-Min Park, Yaojia Jiang, Jiang, Yaojia, Park, Cheol-Min   +5 more
core   +1 more source

Copper(II)-Catalyzed (3+2) Cycloaddition of 2H-Azirines to Six-Membered Cyclic Enols as a Route to Pyrrolo[3,2-c]quinolone, Chromeno[3,4-b]pyrrole, and Naphtho[1,8-ef]indole Scaffolds. [PDF]

Molecules, 2022
Sakharov PA, Rostovskii NV, Khlebnikov AF, Novikov MS.   +3 more
europepmc   +1 more source

The Neber Approach to 2‑(Tetrazol-5-yl)‑2H‑Azirines

, 2016
The synthesis of 2-(tetra­zol-5-yl)-2H-azirines is reported for the first time. Using the Neber approach, β-ketoxime-1H-tetrazoles were converted into the target 2H-azirines bearing phenyl, furan-2-yl, thiophen-2-yl, or pyrrol-2-yl substituents at C-3 ...
Teresa M. V. D. Pinho e Melo (1724932), Ana Lúcia Cardoso (1933843), Américo Lemos (1724944), Francisco Palacios (1447132), Lourdes Gimeno (1933846)   +4 more
core   +1 more source

Synthesis and reactions of functionalized 2H-azirines [PDF]

, 1998
126 p.
openaire   +2 more sources

Photochemische Cycloadditionen von 3-Phenyl-2H-azirinen mit Triphenyl-vinylphosphoniumbromid

, 1974
On irradiation in acetonitrile 3-phenyl-2H-azirines of type 1 react with triphenyl vinyl phosphonium bromide to form in approximative 50% yield 2H-indoles of type 4 (Scheme 7).
Heimgartner, Heinz, Schmid, Hans, Gakis, Nikolas   +2 more
core   +1 more source

Reaction of Diphenyl Phosphorochloridate with Amide Enolates: A New and Convenient Synthesis of 2-Monosubstituted 3-(N-Methyl-N-phenylamino)-2H-azirines

, 1992
Reaction of diphenyl phosphorochloridate with amide enolates and subsequent treatment with NaN3 leads to 2-monosubstituted 3-amino-2H-azirines 5 in moderate yields.
Heinz Heimgartner, José M. Villalgordo, Heimgartner, Heinz, Villalgordo, Jose M   +3 more
core   +1 more source