Results 31 to 40 of about 1,013 (159)
2-[2-(2,6-Dichlorobenzyloxy)-2-phenylethyl]-2H-indazole [PDF]
In the title compound, C22H18Cl2N2O, the indazole ring system is approximately planar [maximum deviation = 0.031 (2) Å], its mean plane is oriented at 3.17 (4) and 19.34 (4)° with respect to the phenyl and benzene rings. In the crystal, weak C—H...π interactions link the molecules into supramolecular chains running along theb-axis direction.
Özel Güven, Özden +4 more
openaire +6 more sources
Tris[2-(2H-indazol-2-yl)ethyl]amine [PDF]
The title tertiary amine, C27H27N7, a potential tripodal ligand for coordination chemistry, crystallizes with the central N atom located on a threefold axis of a trigonal cell. The gauche conformation of the N(amime)—CH2—CH2—N(indazole) chain [torsion angle = −64.2 (2)°] places the pendant 2H-indazole heterocycles surrounding the symmetry axis ...
Saúl Ovalle +4 more
openaire +3 more sources
Current and Future Prospects of Nitro-compounds as Drugs for Trypanosomiasis and Leishmaniasis [PDF]
Interest in nitroheterocyclic drugs for the treatment of infectious diseases has undergone a resurgence in recent years. Here we review the current status of monocyclic and bicyclic nitroheterocyclic compounds as existing or potential new treatments for ...
Alan H. Fairlamb +141 more
core +2 more sources
Photo- and electro-chemical strategies for indazole synthesis
The indazole core is prevalently found in the structures of bioactive molecules, demonstrating promising potential in medicinal chemistry and drug discovery, which therefore has attracted sustained attention from the synthetic community.
Binbin Huang
doaj +1 more source
Direct Arylation in the Presence of Palladium Pincer Complexes [PDF]
Direct arylation is an atom-economical alternative to more established procedures such as Stille, Suzuki or Negishi arylation reactions. In comparison with other palladium sources and ligands, the use of palladium pincer complexes as catalysts or pre ...
Churruca Quincoces, Fátima +4 more
core +1 more source
Green metrics in mechanochemistry [PDF]
F. G. would like to thank the support of Fundacion para el Fomento en Asturias de la Investigacion Cientıfica Aplicada y la Tecnologıa (FICYT) through the Margarita Salas Senior Program (AYUD/2021/59709) and the Ministerio de Ciencia e Innovacion through
Colacino, E. +5 more
core +4 more sources
Combined Gold and Photoredox Catalysis: Synthesis of 3-Alkenyl-2H-Indazoles from 2-Alkynylazobenzenes [PDF]
We disclose the intramolecular synthesis of 3- alkenyl-2H-indazoles from 2-alkynylazobenzenes, promoted by a dual catalysis using AuCl3 and a ruthenium photocatalyst under visible light irradiation.
Mañas Hernández, Clara +1 more
core +1 more source
2,2′-(Propane-1,3-diyl)bis(2H-indazole) [PDF]
The title mol-ecule, C(17)H(16)N(4), is a bis-indazole crystallized in the rare 2H-tautomeric form. Indazole heterocycles are connected by a propane C(3) chain, and the mol-ecule is placed on a general position, in contrast to the analogous compound with a central C(2) ethane bridge, which was previously found to be placed on an inversion center in the
Ovalle Pérez, Saúl +3 more
openaire +3 more sources
Transition Metal Catalyzed Reductive Cyclization Reactions of Nitroarenes and Nitroalkenes [PDF]
Nitroarenes are the entry point for the production of most nitrogen-containing aromatic compounds. Thus, any transformation that leads directly from them to the final product allows saving one or more synthetic steps. This review deals with homogeneously
D.R. Ramadan, F. Ferretti, F. Ragaini
core +1 more source
Systematic overview of pyrazole functionalization reactions from C‐5 to N−H. It covers different strategies, from traditional cross‐coupling of prefunctionalized pyrazoles to more efficient direct functionalizations. This review briefly and systematically overviews C–H and N–H functionalization reactions of pyrazoles, aimed at creating new CC and C ...
Karolina Dzedulionytė Müldür +3 more
wiley +1 more source

