Results 121 to 130 of about 91,641,710 (291)

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Synthesis of Graft Copolymers Containing Biodegradable Poly(3-hydroxybutyrate) Chains

, 2016
Synthesis of Graft Copolymers Containing Biodegradable Poly(3-hydroxybutyrate ...
Piotr Dacko (2501833), Izabela Goebel (2501830), Joanna Rydz (2501836), Dorota Neugebauer (1459825), Marek Kowalczuk (703904)   +4 more
core   +1 more source

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

Obesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee, Caroline M. Apovian, Nawfal Istfan   +2 more
wiley   +1 more source

3-Hydroxybutyrate alleviates septic liver injury by promoting macrophage polarization from M1 to M2

生物医学转化
Objective To investigate the therapeutic effects and underlying mechanisms of the metabolite 3- hydroxybutyrate (3HB) in a cecal ligation and puncture (CLP)-induced sepsis model in mice.
Hu Jingjuan, Deng Fan, Sun Qishun, Min Yue, Feng Siyuan, Wu Ling, Chen Xiaofeng, Liu Kexuan   +7 more
doaj   +1 more source

Production of poly(3-hydroxybutyrateco-4-hydroxybutyrate) in recombinant Escherichia coli grown on glucose

, 1997
A recombinant Escherichia coli strain has been developed that produces poly(3-hydroxybutyrate-co-4-hydroxybu-tyrate) when grown in complex medium containing glucose. This has been accomplished by introducing into E.
Henry E Valentin, Douglas Dennis, Henry E. Valentin   +2 more
core   +1 more source

Development of Cellulosic Bioplastic‐Based Biocomposites for Biodegradable Packaging Applications: Effect of High Acetyl Content and High Filler Loading

Polymer Engineering &Science, EarlyView.
Schematic representation of the development of cellulosic bioplastic‐based biocomposites via reactive extrusion and injection molding, demonstrating improved oxygen and water vapor barrier properties for biodegradable packaging applications. ABSTRACT Cellulosic bioplastics have attained significant interest because of their biodegradability and ...
Reshma Krishnan, Manjusri Misra, Amar K. Mohanty   +2 more
wiley   +1 more source

Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects

Frontiers in Nutrition
IntroductionThe brain uses ketones, mainly 3-hydroxybutyrate (3-HB), as an alternative energy source. Therefore, oral intake of 3-HB may help maintain brain health.
Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama   +12 more
doaj   +1 more source

Electrospun conducting polymers: recent trends and the transition towards a sustainable future

Polymer International, EarlyView.
This review discusses the electrospinning of conducting polymers, detailing procedures, fibrous morphologies, improved properties, applications in electronics, and challenges, while outlining future directions for nanofibre‐based devices in various fields.
Xenofon Karagiorgis, Sofia Sandhu, Peter J. Skabara, Ravinder Dahiya   +3 more
wiley   +1 more source

Laboratory Research of Degradation of Polyhydroxyalkanoates of Different Chemical Structure in Soil [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2015
Degradation of three types of polyhydroxyalkanoates (PHAs) was studied in the laboratory conditions in the field soil at two temperature regimes during 35 days.
Olga N. Vinogradova, Daria A. Syrvacheva
doaj  

Towards greener yttrium‐catalyzed ring‐opening polymerization via an all‐terpene reaction concept

Polymer International, EarlyView.
Development of a terpene‐based catalytic system for ring‐opening polymerization of bio‐based lactones that reveals the steric effects of the nucleophile on initiation and alkoxide exchange, while simultaneously enabling post‐polymerization functionalization.
Lea‐Sophie Hornberger, Jonas App, Caroline Sophie Pottgiesser, Friederike Adams   +3 more
wiley   +1 more source