Virulence-inhibitory activity of the degradation product 3-hydroxybutyrate explains the protective effect of poly-β-hydroxybutyrate against the major aquaculture pathogen Vibrio campbellii [PDF]
Scientific Reports, 2018 The bacterial storage compound poly-β-hydroxybutyrate, a polymer of the short-chain fatty acid 3-hydroxybutyrate, has been reported to protect various aquatic animals from bacterial disease. In order to obtain a better mechanistic insight, we aimed to (1)
Tom Defoirdt +2 more
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A Forward-Design Approach to Increase the Production of Poly-3-Hydroxybutyrate in Genetically Engineered Escherichia coli [PDF]
, 2015 Biopolymers, such as poly-3-hydroxybutyrate (P(3HB)) are produced as a carbon store in an array of organisms and exhibit characteristics which are similar to oil-derived plastics, yet have the added advantages of biodegradability and biocompatibility ...
Bower, I +12 more
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Metabolites, 2023 Beta-ketothiolases are involved in the beta-oxidation of fatty acids and the metabolism of hormones, benzenoids, and hydroxybutyrate. The expression of bacterial beta-ketothiolase in flax (Linum usitatissimum L.) results in an increase in endogenous beta-
Justyna Mierziak +9 more
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3-Hydroxybutyrate as a Metabolite and a Signal Molecule Regulating Processes of Living Organisms
Biomolecules, 2021 3-hydroxybutyrate (3-HB) as a very important metabolite occurs in animals, bacteria and plants. It is well known that in animals, 3-HB is formed as a product of the normal metabolism of fatty acid oxidation and can therefore be used as an energy source ...
Justyna Mierziak +2 more
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Synthesis of Poly(3-hydroxybutyrate) by Immobilized Poly(3-hydroxybutyrate) Synthase [PDF]
Polymer Journal, 2003 At present, biodegradable and biocompatible polymers are being widely sought by materials industries, and poly(3-hydroxyalkanoate) (PHA) appears to be one of the most promising material sources of such polymers. Poly(3-hydroxybutyrate) (PHB) is a typical PHA and has been investigated in detail.
Kenji Tajima +3 more
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Bioengineering, 2022 A new polythioester (PTE), poly(3-mercapto-2-methylpropionate) [P(3M2MP)], and its copolymer with 3-hydroxybutyrate (3HB) were successfully biosynthesized from 3-mercapto-2-methylpropionic acid as a structurally-related precursor.
Lucas Vinicius Santini Ceneviva +6 more
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(Bio)degradable polymeric materials for sustainable future—Part 3: Degradation studies of the PHA/wood flour-based composites and preliminary tests of antimicrobial activity [PDF]
, 2020 © 2020 The Authors. Published by MDPI. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.3390/ma13092200The need for a ...
Janeczek, Henryk +10 more
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Microbial Cell Factories, 2018 Background High production cost of bioplastics polyhydroxyalkanoates (PHA) is a major obstacle to replace traditional petro-based plastics. To address the challenges, strategies towards upstream metabolic engineering and downstream fermentation ...
Jing Chen +4 more
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In silico Assessment of Pharmacological Profile of Low Molecular Weight Oligo-Hydroxyalkanoates
Frontiers in Bioengineering and Biotechnology, 2020 Polyhydroxyalkanoates (PHAs) are a large class of polyesters that are biosynthesized by microorganisms at large molecular weights (Mw > 80 kDa) and have a great potential for medical applications because of their recognized biocompatibility.
Diana Larisa Roman +4 more
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Microbial degradation of poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in soils [PDF]
Applied and Environmental Microbiology, 1993 The microbial degradation of tensile test pieces made of poly(3-hydroxybutyrate) [P(3HB)] or a copolymer of 90% 3-hydroxybutyric acid and 10% 3-hydroxyvaleric acid was studied in soils incubated at a constant temperature of 15, 28, or 40 degrees C for up to 200 days.
Mergaert, Joris +4 more
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