Results 1 to 10 of about 20,093,212 (172)

Mechanical Properties of 3-Hydroxybutyric Acid-Induced Vesicles

open access: yesMolecules, 2023
The vesicle mechanical behaviors were studied upon its exposure to 3-hydroxybutyric acid using an atomic force microscope (AFM). Dipalmitoylphosphatidylcholine (DPPC) and 3-hydroxybutyric acid were used to manufacture the vesicles at their desired ratio.
Seung Jun Jung   +2 more
doaj   +5 more sources

đťś·-hydroxybutyric acid attenuates oxidative stress and improves markers of mitochondrial function in the HT-22 hippocampal cell line [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
Ketone bodies have been the topic of research for their possible therapeutic neurotropic effects in various neurological diseases such as Parkinson’s disease, dementia, and seizures.
Mohammed Majrashi   +11 more
doaj   +1 more source

Serum Metabolomic Study on the Difference between Mild and Severe Acute Pancreatitis Based on Liquid Chromatography-tandem Mass Spectrometry [PDF]

open access: yesZhongguo quanke yixue, 2023
Background Mild acute pancreatitis (MAP) has a certain probability of transforming into severe acute pancreatitis (SAP) . Once SAP occurs, it will cause greater harm to patients. It is meaningful for diagnosis and treatment of pancreatitis to explore the
HUANG Xiangping, WU Ling, TAN Chaochao
doaj   +1 more source

Multi-Omics Analyses Reveal the Mechanisms of Early Stage Kidney Toxicity by Diquat

open access: yesToxics, 2023
Diquat (DQ), a widely used bipyridyl herbicide, is associated with significantly higher rates of kidney injuries compared to other pesticides. However, the underlying molecular mechanisms are largely unknown.
Huazhong Zhang   +7 more
doaj   +1 more source

Targeted and untargeted metabolomic approach for GDM diagnosis

open access: yesFrontiers in Molecular Biosciences, 2023
Gestational diabetes mellitus (GDM) is a disorder which manifests itself for the first time during pregnancy and is mainly connected with glucose metabolism.
Izabela Burzynska-Pedziwiatr   +14 more
doaj   +1 more source

Identification of Morphine and Heroin-Treatment in Mice Using Metabonomics

open access: yesMetabolites, 2021
Although heroin and morphine are structural analogues and morphine is a metabolite of heroin, it is not known how the effect of each substance on metabolites in vivo differs. Heroin and morphine were administered to C57BL/6J mice in increasing doses from
Wuhuan Lu   +9 more
doaj   +1 more source

Three new O-isocrotonyl-3-hydroxybutyric acid congeners produced by a sea anemone-derived marine bacterium of the genus Vibrio

open access: yesBeilstein Journal of Organic Chemistry, 2020
Liquid cultures of Vibrio sp. SI9, isolated from the outer tissue of the sea anemone Radianthus crispus, was found to produce three new O-isocrotonyl-3-hydroxybutyric acid derivatives, O-isocrotonyl-3-hydroxypentanoic acid (1), O-isocrotonyl-3 ...
Dandan Li   +4 more
doaj   +1 more source

The Gut Microbiota and Associated Metabolites Are Altered in Sleep Disorder of Children With Autism Spectrum Disorders

open access: yesFrontiers in Psychiatry, 2020
BackgroundAutism spectrum disorder (ASD) is a type of neurodevelopmental disease that is frequently accompanied by sleep disorder. Herein, we investigated changes in the gut microbiota and its metabolites correlated with core symptoms and sleep problems ...
Xueying Hua   +13 more
doaj   +1 more source

SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum

open access: yesiScience, 2020
Summary: COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there is little information on how SARS-CoV-2 affects metabolism.
Chiara Bruzzone   +18 more
doaj   +1 more source

Investigation of the idiosyncratic hepatotoxicity of Polygonum multiflorum Thunb. through metabolomics using GC-MS

open access: yesBMC Complementary Medicine and Therapies, 2021
Background The idiosyncratic hepatotoxicity of Polygonum multiflorum (PM) has attracted considerable interest, but the idiosyncratically hepatotoxic components and endogenous metabolite changes resulting from idiosyncratic hepatotoxicity of PM are not ...
Yan Lin   +7 more
doaj   +1 more source

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