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Mechanical Properties of 3-Hydroxybutyric Acid-Induced Vesicles [PDF]

open access: yesMolecules, 2023
The vesicle mechanical behaviors were studied upon its exposure to 3-hydroxybutyric acid using an atomic force microscope (AFM). Dipalmitoylphosphatidylcholine (DPPC) and 3-hydroxybutyric acid were used to manufacture the vesicles at their desired ratio.
Seung Jun Jung   +2 more
doaj   +6 more sources

Three new O-isocrotonyl-3-hydroxybutyric acid congeners produced by a sea anemone-derived marine bacterium of the genus Vibrio [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2020
Liquid cultures of Vibrio sp. SI9, isolated from the outer tissue of the sea anemone Radianthus crispus, was found to produce three new O-isocrotonyl-3-hydroxybutyric acid derivatives, O-isocrotonyl-3-hydroxypentanoic acid (1), O-isocrotonyl-3 ...
Dandan Li   +4 more
doaj   +2 more sources

Production of (R)-3-hydroxybutyric acid by Arxula adeninivorans. [PDF]

open access: yesAMB Express, 2017
(R)-3-hydroxybutyric acid can be used in industrial and health applications. The synthesis pathway comprises two enzymes, β-ketothiolase and acetoacetyl-CoA reductase which convert cytoplasmic acetyl-CoA to (R)-3-hydroxybutyric acid [(R)-3-HB] which is released into the culture medium.
Biernacki M   +6 more
europepmc   +4 more sources

Antibiotic-free Wenchang chickens may promote blood levels of B vitamins by modulating the gut microbiota: An integrated analysis of cecal content metagenomics and serum metabolomics [PDF]

open access: yesPoultry Science
Through the selective breeding of superior strains, livestock and poultry can achieve enhanced disease resistance and production performance, thereby improving farming efficiency and increasing chicken meat yield.
Shifan Deng   +7 more
doaj   +2 more sources

Development of a semi-endogenous PRT-based expression system for Methylotuvimicrobium alcaliphilum and its application to enhance 3-hydroxybutyric acid production from methanol [PDF]

open access: yesJournal of Biological Engineering
Background Endogenous expression systems, such as those incorporating promoters, ribosome-binding sites (RBS), and terminators (i.e., PRT systems), have been developed for various bacterial host strains.
Khoi Nhat Pham, Eun Yeol Lee
doaj   +2 more sources

Molecular characterization, clinical phenotype, and neurological outcome of twelve Palestinian children with beta-ketothiolase deficiency: report of two novel variants in the ACAT1 gene [PDF]

open access: yesBMC Medical Genomics
Background Beta-ketothiolase deficiency (mitochondrial acetoacetyl-CoA thiolase, T2) deficiency (OMIM #203750, *607809) is an autosomal recessive disorder of isoleucine catabolism and ketone body utilization.
Imad M. Dweikat   +5 more
doaj   +2 more sources

𝜷-hydroxybutyric acid attenuates oxidative stress and improves markers of mitochondrial function in the HT-22 hippocampal cell line [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
Ketone bodies have been the topic of research for their possible therapeutic neurotropic effects in various neurological diseases such as Parkinson’s disease, dementia, and seizures.
Mohammed Majrashi   +11 more
doaj   +1 more source

Serum Metabolomic Study on the Difference between Mild and Severe Acute Pancreatitis Based on Liquid Chromatography-tandem Mass Spectrometry [PDF]

open access: yesZhongguo quanke yixue, 2023
Background Mild acute pancreatitis (MAP) has a certain probability of transforming into severe acute pancreatitis (SAP) . Once SAP occurs, it will cause greater harm to patients. It is meaningful for diagnosis and treatment of pancreatitis to explore the
HUANG Xiangping, WU Ling, TAN Chaochao
doaj   +1 more source

Microfibrillated Cellulose Grafted with Metacrylic Acid as a Modifier in Poly(3-hydroxybutyrate) [PDF]

open access: yesPolymers, 2021
This work proposes a new method for obtaining poly(3-hydroxybutyrate) (PHB)/microfibrillated cellulose (MC) composites with more balanced properties intended for the substitution of petroleum-based polymers in packaging and engineering applications. To achieve this, the MC surface was adjusted by a new chemical route to enhance its compatibility with ...
Marius Stelian Popa   +8 more
openaire   +2 more sources

Multi-Omics Analyses Reveal the Mechanisms of Early Stage Kidney Toxicity by Diquat

open access: yesToxics, 2023
Diquat (DQ), a widely used bipyridyl herbicide, is associated with significantly higher rates of kidney injuries compared to other pesticides. However, the underlying molecular mechanisms are largely unknown.
Huazhong Zhang   +7 more
doaj   +1 more source

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