Results 21 to 30 of about 1,374,074 (257)

Identification of Morphine and Heroin-Treatment in Mice Using Metabonomics

open access: yesMetabolites, 2021
Although heroin and morphine are structural analogues and morphine is a metabolite of heroin, it is not known how the effect of each substance on metabolites in vivo differs. Heroin and morphine were administered to C57BL/6J mice in increasing doses from
Wuhuan Lu   +9 more
doaj   +1 more source

Osteoblasts and fibroblasts attachment to poly(3-hydroxybutyric acid-co-3-hydrovaleric acid) (PHBV) film and electrospun scaffolds.

open access: yesMaterials Science and Engineering C: Materials for Biological Applications, 2020
The cellular response is the most crucial in vitro research. Materials' biocompatibility is determined based on cell proliferation and growth. Moreover, the topography of the scaffold surface is the key to enhance cell attachment and anchoring that ...
Łukasz Kaniuk   +3 more
semanticscholar   +1 more source

The Gut Microbiota and Associated Metabolites Are Altered in Sleep Disorder of Children With Autism Spectrum Disorders

open access: yesFrontiers in Psychiatry, 2020
BackgroundAutism spectrum disorder (ASD) is a type of neurodevelopmental disease that is frequently accompanied by sleep disorder. Herein, we investigated changes in the gut microbiota and its metabolites correlated with core symptoms and sleep problems ...
Xueying Hua   +13 more
doaj   +1 more source

Dynamic Metabolic Analysis of Cupriavidus necator DSM545 Producing Poly(3-hydroxybutyric acid) from Glycerol

open access: yesProcesses, 2020
Cupriavidus necator DSM 545 can utilise glycerol to synthesise poly(3-hydroxybutyric acid) under unbalanced growth conditions, i.e., nitrogen limitation. To improve poly(3-hydroxybutyric acid) (PHB) batch production by C.
Chenhao Sun   +3 more
semanticscholar   +1 more source

Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct 'on spot' derivatization [PDF]

open access: yes, 2010
The objective of this study was the development of an accurate and sensitive method for the determination of gamma-hydroxybutyric acid (GHB) in dried whole blood samples using a GC-MS method.
Ingels, Ann-Sofie   +2 more
core   +1 more source

SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum

open access: yesiScience, 2020
Summary: COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there is little information on how SARS-CoV-2 affects metabolism.
Chiara Bruzzone   +18 more
doaj   +1 more source

Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem®)-treated narcoleptic patients using dried blood spot sampling at home : an exploratory study [PDF]

open access: yes, 2013
Background: Gamma-hydroxybutyric acid (GHB), well known as a party drug, especially in Europe, is also legally used (sodium oxybate, Xyrem (R)) to treat a rare sleep disorder, narcolepsy with cataplexy.
Hertegonne, Katrien   +3 more
core   +1 more source

Investigation of the idiosyncratic hepatotoxicity of Polygonum multiflorum Thunb. through metabolomics using GC-MS

open access: yesBMC Complementary Medicine and Therapies, 2021
Background The idiosyncratic hepatotoxicity of Polygonum multiflorum (PM) has attracted considerable interest, but the idiosyncratically hepatotoxic components and endogenous metabolite changes resulting from idiosyncratic hepatotoxicity of PM are not ...
Yan Lin   +7 more
doaj   +1 more source

Chemical Constituents and Anti-Angiogenic Principles from a Marine Algicolous Penicillium sumatraense SC29

open access: yesMolecules, 2022
In this study, a marine brown alga Sargassum cristaefolium-derived fungal strain, Penicillium sumatraense SC29, was isolated and identified. Column chromatography of the extracts from liquid fermented products of the fungal strain was carried out and led
Hsiao-Yang Hsi   +9 more
doaj   +1 more source

Ulva rigida Valorization into Poly(3-hydroxybutyrate), Organic Acids and Functional Ingredients

open access: yesMarine Drugs, 2023
Halomonas elongata 1H9T is a moderate halophilic strain able to produce poly(3-hydroxybutyrate) (P(3HB)), a biodegradable plastic, and gluconic acid, a valuable organic acid with wide industrial applications. In this work, the green alga Ulva rigida was used as platform to produce cultivation substrates for microbial conversion as well as functional ...
Tânia Leandro   +6 more
openaire   +4 more sources

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