Results 31 to 40 of about 20,093,212 (172)

Why Do High-Risk Patients Develop or Not Develop Coronary Artery Disease? Metabolic Insights from the CAPIRE Study

Metabolites, 2022
Traditional cardiovascular (CV) risk factors (RFs) and coronary artery disease (CAD) do not always show a direct correlation. We investigated the metabolic differences in a cohort of patients with a high CV risk profile who developed, or did not develop,
Martino Deidda, Antonio Noto, Christian Cadeddu Dessalvi, Daniele Andreini, Felicita Andreotti, Eleuterio Ferrannini, Roberto Latini, Aldo P. Maggioni, Marco Magnoni, Giuseppe Mercuro, on behalf of the CAPIRE Investigators   +10 more
doaj   +1 more source

The metabolic effects of intermittent versus continuous feeding in critically ill patients

Scientific Reports, 2023
Intermittent (or bolus) feeding regimens in critically ill patients have been of increasing interest to clinicians and scientists. Changes in amino acid, fat and carbohydrate metabolites over time might yet deliver other benefits (e.g.
D. Wilkinson, I. J. Gallagher, A. McNelly, D. E. Bear, N. Hart, H. E. Montgomery, A. Le Guennec, M. R. Conte, T. Francis, S. D. R. Harridge, P. J. Atherton, Z. A. Puthucheary   +11 more
doaj   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

Advanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu, Jiaqi Zou, Geng Han, Mengyao Zhao, Ting Luo, Xiangru Feng, Liangliang Zhu, Yijia Chen, Xiaoguo Ji, Jiayang Jin, Liming Zhao   +10 more
wiley   +1 more source

Estudo de estratégias de produção de poli(3-hidroxibutirato-co-3-hidroxivalerato) por ralstonia eutropha utilizando substratos de baixo custo e ácido propiônico / [PDF]

, 2000
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.O desenvolvimento de estratégias de produção de poli(3-hidroxibutirato-co-3-hidroxivalerato) a partir de substratos de baixo custo buscando melhorar a incorporação de ...
Marangoni, Cintia
core  

Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain [PDF]

, 2001
2-Hydroxybutyric acid appears at high concentrations in situations related to deficient energy metabolism (e.g., birth asphyxia) and also in inherited metabolic diseases affecting the central nervous system during neonatal development, such as "cerebral"
Wyse, A.T.S., A.R. Silva, Dutra-Filho, C.S., M. Wajner, A.T.S. Wyse, C.M.D. Wannmacher, Wajner, M., C. Ruschel, C.S. Dutra-Filho, Ruschel, C., C. Helegda, Helegda, C., Wannmacher, C.M.D., Silva, A.R.   +13 more
core   +4 more sources

Sirtuin 3 regulation: a target to alleviate β-hydroxybutyric acid-induced mitochondrial dysfunction in bovine granulosa cells

Journal of Animal Science and Biotechnology, 2023
Background During the transition period, the insufficient dry matter intake and a sharply increased in energy consumption to produce large quantities of milk, high yielding cows would enter a negative energy balance (NEB) that causes an increase in ...
Shanjiang Zhao, Jianfei Gong, Yi Wang, Nuo Heng, Huan Wang, Zhihui Hu, Haoyu Wang, Haobo Zhang, Huabin Zhu   +8 more
doaj   +1 more source

Near‐infrared light‐activated aptamer‐based nanoprobe for spatiotemporally resolved detection of L‐lactate in colorectal cancer

BMEMat, EarlyView.
A near‐infrared (NIR) light‐activated “lock‐key” nanodevice is reported for spatiotemporally resolved detection of intratumoral L‐lactate. The system stays silent until deep‐penetrating NIR light remotely unlocks its function, allowing for precise sensing within tumors.
Siyu Pan, Xuanyi Lu, Wenjie Yang, Yunhui Peng, Lingfu Deng, Shuai Zha, Xueyang Fang, Guochen Bao, Lijun Jiang   +8 more
wiley   +1 more source

Produção e caracterização de Poli(3-Hidroxibutirato-co-3-hidroxivalerato) por cupriavidus necator em melaço cítrico [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Alimentos, Florianópolis, 2009.Poli(3-hidroxibutirato-co-3-hidrohivalerato) [P(3HB-co-3HV)] é um biopolímero acumulado ...
Farias, Daniele
core  

Assessment of mass spectrometric indicators of organic acids metabolism in children with sarcopenia on the background of protein-energy insufficiency. Pilot study

Acta Biomedica Scientifica
Introduction. The geriatric problem of sarcopenia is relevant for both therapists and pediatricians. Secondary sarcopenia is diagnosed at any age in severe diseases, as well as muscle loss and muscle strength due to protein-energy malnutrition (PEM) or ...
V. P. Novikova, A. N. Zavyalova, M. N. Yakovleva, E. L. Strukov, I. V. Kukes, T. D. Lunegov   +5 more
doaj   +1 more source