Results 191 to 200 of about 18,203,152 (258)
ABSTRACT Introduction Global awareness to chemsex, a specific form of sexualized psychoactive substance (“chems”) use among gay, bisexual and other men who have sex with men (gbMSM), is increasing. We aimed to assess prevalence, patterns and implications of “chems” use on chemsex‐related outcomes.
Bashkim Jaha +14 more
wiley +1 more source
Medium Chain Acyl‐CoA Dehydrogenase Deficiency; an Unexpected Cause of Neonatal Ketoacidosis
ABSTRACT Medium‐chain acyl‐CoA dehydrogenase deficiency (MCADD) classically presents with hypoketotic hypoglycaemia; however, this presentation is now rare following the introduction of newborn screening. While children with MCADD may produce some ketones, severe ketoacidosis has not been previously described.
Nazreen Kamarus Jaman +7 more
wiley +1 more source
PLA Foaming Process and Its Research Progress
Poly(lactic acid) (PLA) foaming is mapped from molecular structure and gas–polymer interactions to extrusion, autoclave, injection, and 3D‐printing routes. The review reveals how crystallization, rheology, pressure history, and flow govern cellular architecture, while highlighting intelligent control, sustainable blowing agents, and multimodal ...
Guiyin Xia +3 more
wiley +1 more source
Ferroptosis: Newly Emerged Regulator for Human Disease
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao +4 more
wiley +1 more source
The Health Benefits of Exercise: Molecular and Cellular Mechanisms
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying +12 more
wiley +1 more source
Amino Acid Metabolism in Health and Disease
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su +7 more
wiley +1 more source
GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework
ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler +2 more
wiley +1 more source
1H NMR–based serum metabolomics was employed to identify AMI differential biomarkers and associated metabolic pathways. A diagnostic model evaluated via ROC analysis demonstrated robust performance of these biomarkers, thereby providing novel insights into the pathophysiological mechanisms underlying AMI. ABSTRACT Acute myocardial infarction (AMI) is a
Bing He +7 more
wiley +1 more source
Nano zinc oxide supplementation did not significantly affect TOS, TAS or OSI in transition period Lacaune ewes. However, treatment related responses were observed for BHBA, phosphorus and total cholesterol, suggesting limited metabolic effects that require cautious interpretation.
Gaye Bulut +2 more
wiley +1 more source
Adipose tissue‐specific deficiency of eIF2A is insufficient to reproduce the metabolic defects observed in total‐body eIF2A knockout mice, suggesting that the systemic metabolic effects observed in these mice may arise from coordinated functions across multiple organs.
Adedeji Isaac Adeloye +13 more
wiley +1 more source

