Results 211 to 220 of about 54,789 (273)

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Biosynthesis of poly(3-hydroxybutyrate-<i>co</i>-lactate) using an NADH regeneration strategy in <i>E. coli</i>. [PDF]

Biodes Res
Wu J, Gong X, Guo P, Shang Y, Luo Y, Wu H.   +5 more
europepmc   +1 more source

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan, Eva Troyano‐Rodriguez, Jennifer Ihuoma, Sharon Negri, Rakesh Rudraboina, Aleksandra Kosmider, Shantipriya Awasthi, Priya Balasubramanian, Shannon Conley, Andriy Yabluchanskiy, Anna Csiszar, Zoltan Ungvari, Rafael de Cabo, Stefano Tarantini   +13 more
wiley   +1 more source

Emergency department presentations, hospitalisations and police seizure data related to gamma‐hydroxybutyrate (GHB) in New South Wales, Australia, from 2015 to 2024

Addiction, Volume 121, Issue 2, Page 305-315, February 2026.
Abstract Background and aims Gamma‐hydroxybutyrate (GHB) is an endogenous neurochemical and illicit synthetic drug. Its precursors, gamma‐butyrolactone (GBL) and 1,4‐butanediol (1,4‐BD), are often used as substitutes. We aimed to describe GHB‐related harms in New South Wales (NSW), Australia.
Krista J. Siefried, Janette L. Smith, Christine A. Harvey, Anthony Nedanoski, Jared A. Brown, Una Cullinan, Nadine Ezard, Thanjira Jiranantakan, Darren M. Roberts, Jonathan Brett   +9 more
wiley   +1 more source

Biocontrol Potential of Poly(3-hydroxybutyrate) Fibers Functionalized with Chitooligosaccharide/<i>Bacillus subtilis</i> Using Electrospinning and Electrospraying. [PDF]

Polymers (Basel)
Stoyanova N, Nachev N, Naydenov M, Valcheva I, Spasova M, Stoilova O.   +5 more
europepmc   +1 more source

The Effect of Acetic Acid as a Solvent on the Structure and Properties of Poly(3-hydroxybutyrate)-Based Dried Gels. [PDF]

Gels
Zhuikov V, Zhuikova Y.
europepmc   +1 more source

Effect of a homemade diet compared to a commercial diet on glycaemic variability and glycaemic control assessed by continuous glucose monitoring system in diabetic dogs: a randomised crossover study

Journal of Small Animal Practice, Volume 67, Issue 2, Page 172-180, February 2026.
Objectives To evaluate the effects of a homemade diet and a commercial diet on glycaemic control and glycaemic variability of diabetic dogs monitored with the FreeStyle Libre continuous glucose monitoring system. Materials and Methods Prospective randomised crossover study including ten client‐owned diabetic dogs on insulin treatment with good ...
A. M. Tardo, C. G. Vecchiato, E. Gherlinzoni, A. Corsini, S. Corradini, F. Del Baldo, G. Biagi, F. Fracassi   +7 more
wiley   +1 more source

Mono‐Materials Created by Engineering a Continuum of P3HB Stereomicrostructures in a One‐Step Catalytic Process

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
Diastereomeric mixtures of diolide were polymerized to P3HB mono‐materials that behave like thermoplastics, thermoplastic elastomers, and pressure‐sensitive adhesives, which were then combined to create all‐P3HB mono‐material tapes. Abstract Multi‐material products that combine multiple complementary polymers can create products with desired ...
Ethan C. Quinn, Celine R. Parker, Maëlle T. Gace, Minjung Lee, Shu Xu, Ethan Poppen, Zhen Zhang, Deepak K. Barange, Meltem Urgun‐Demirtas, Nicholas Rorrer, Eugene Y.‐X. Chen   +10 more
wiley   +2 more sources

Natural Low-Eutectic Solvent Co-Culture-Assisted Whole-Cell Catalyzed Synthesis of Ethyl (<i>R</i>)-4-Chloro-3-Hydroxybutyrate. [PDF]

Molecules
Wang Y, Liu B, Dai Y, Tao Z, Tang L, Ou Z.   +5 more
europepmc   +1 more source

Impact of time‐restricted feeding on metabolic health and adipose tissue metabolism in aged female mice with high‐fat diet‐induced obesity

The Journal of Physiology, Volume 604, Issue 3, Page 1137-1157, 1 February 2026.
Abstract figure legend A 10 week time‐restricted feeding (TRF) regimen was implemented in aged female mice following 12 weeks of high‐fat diet (HFD) feeding. TRF partially reversed HFD‐induced weight and fat mass gain, reduced adipocyte size and increased size heterogeneity in white adipose tissue.
Theresa Bushman, Hongming Su, Xiaoli Chen   +2 more
wiley   +1 more source