The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
The impact of space flight on survival and interaction of Cupriavidus metallidurans CH34 with basalt, a volcanic moon analog rock [PDF]
, 2017 Microbe-mineral interactions have become of interest for space exploration as microorganisms could be used to biomine from extra-terrestrial material and extract elements useful as micronutrients in life support systems.
Bo Byloos +9 more
core +2 more sources
Chinese Journal of Magnetic Resonance, 2019 Molecular dynamics of semi-crystalline poly(3-hydroxybutyrate) (PHB) and copolymers poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) containing 5 wt.% (PHBV5) and 12 wt.% (PHBV12) 3-hydroxyvalerate monomer was studied with solid-state NMR spectroscopy.
XU Guang-yong +3 more
doaj +1 more source
Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs [PDF]
, 2012 BACKGROUND: Fibroblast growth factor 21 (FGF21), whose expression is induced by peroxisome proliferator-activated receptor alpha (PPARalpha), has been recently identified as a novel metabolic regulator which plays a crucial role in glucose homeostasis ...
Eder, Klaus +2 more
core +2 more sources
Microbial Degradation of Poly(3-Hydroxybutyrate) and Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) in Soils [PDF]
Applied and Environmental Microbiology, 1994 [This corrects the article on p. 3236 in vol. 59.].
openaire +2 more sources
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Journal of Experimental Nanoscience, 2020 In this study, adsorption treatment of phenol pollutant using electrospun poly(3-hydroxybutyrate) [P(3HB)] and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) [P(3HB-co-3HHx)] is highlighted for the first time. Both P(3HB) and P(3HB-co-3HHx) were extracted
Ainil Hawa +4 more
doaj +1 more source
Acta Chimica Slovenica, 2020 This study aimed to prepare poly (3-hydroxybutyrate-co-3-hydroxyvalerate), biocomposites with incorporating various percentages of calcium carbonate using extrusion processing.
Semra Kirboga, Mualla Öner
doaj +1 more source
3-Hydroxybutyrate Derived from Poly-3-Hydroxybutyrate Mobilization Alleviates Protein Aggregation in Heat-Stressed Herbaspirillum seropedicae SmR1 [PDF]
Applied and Environmental Microbiology, 2020 Bacteria are subject to abrupt changes in environmental conditions affecting their growth, requiring rapid adaptation. Increasing the concentration of some metabolites can protect bacteria from hostile conditions that lead to protein denaturation and precipitation, as well as damage to plasma membranes.
Luis Paulo Silveira Alves +6 more
openaire +2 more sources
Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals [PDF]
, 2013 17 β-Hydroxysteroid dehydrogenase type 1 (17 β -HSD1) catalyzes the conversion of estrone to the potent estrogen estradiol. 17 β -HSD1 is highly expressed in breast and ovary tissues and represents a prognostic marker for the tumor progression and ...
Atanasov, Atanas G. +3 more
core +3 more sources