Results 61 to 70 of about 91,641,710 (291)

¹H NMR Based Metabolomics in Human Sepsis and Healthy Serum

Metabolites, 2020
Early diagnosis is essential but challenging in severe sepsis. Quantifying and comparing metabolite concentrations in serum has been suggested as a new diagnostic tool.
Henna Jaurila, Vesa Koivukangas, Marjo Koskela, Fiia Gäddnäs, Sami Myllymaa, Arja Kullaa, Tuula Salo, Tero I. Ala-Kokko   +7 more
doaj   +1 more source

Production of poly (3-hydroxybutyrate-co-4-hydroxybutyrate) by Burkholderia sacchari using wheat straw hydrolysates and gamma-butyrolactone [PDF]

, 2014
“NOTICE: this is the author’s version of a work that was accepted for publication in International Journal of Biological Macromolecules. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Cesário, M. Teresa, Van Keulen, Frederik, Raposo, Rodrigo S., Ferreira, Bruno S., Telo, João P., Almeida, M. Catarina M. D. de, Fonseca, M. Manuela R. da   +6 more
core   +1 more source

Indole‐3‐Acetic Acid Protects Bovine Hepatocytes Against Palmitic Acid‐Induced Lipid Accumulation and ER Stress Through SIRT3

Animal Research and One Health, EarlyView.
Cows with ketosis during the perinatal period often experience damage to the liver, a core metabolic organ, thereby exacerbating the disease's inherent vicious cycle. This study indicates that serum 3‐IAA concentrations were reduced in ketotic cows and show a significant negative correlation with hepatic TG content.
Dandan Qi, Chenchen Zhao, Guiying Li, Jinxia Li, Menglin Liu, Fanrong Kong, Enzhu Li, Jie Gao, Wenqi Liao, Akos Kenez, Wenwen Gao, Yuxiang Song, Xiliang Du, Guowen Liu, Xinwei Li, Lin Lei   +15 more
wiley   +1 more source

The use of sodium DL-3-Hydroxybutyrate in severe acute neuro-metabolic compromise in patients with inherited ketone body synthetic disorders

Orphanet Journal of Rare Diseases, 2020
Background Ketone bodies form a vital energy source for end organs in a variety of physiological circumstances. At different times, the heart, brain and skeletal muscle in particular can use ketones as a primary substrate.
Kaustuv Bhattacharya, Walid Matar, Adviye Ayper Tolun, Beena Devanapalli, Sue Thompson, Troy Dalkeith, Kate Lichkus, Michel Tchan   +7 more
doaj   +1 more source

Reducing Cooling Costs for Sustainable Food Biomanufacturing With Thermotolerant Cupriavidus necator H16 Mutant

Biotechnology and Bioengineering, EarlyView.
With a thermotolerant C. necator mutant the SCP production costs can be decreased by $0.98/kg. ABSTRACT Autotrophic CO2 conversion to Single Cell Protein (SCP) using H2 and O2 is gaining commercial traction for food and feed production. Cupriavidus necator H16 is a key chassis organism for this “knallgas” fermentation, but industrial operation is ...
Lars Puiman, James Kemp Heffernan, Esteban Marcellin   +2 more
wiley   +1 more source

Isolation and Characterization of Random Citrate Synthase Variants That Increase Acetate Generation by Escherichia coli

Biotechnology and Bioengineering, EarlyView.
ABSTRACT A method to select Escherichia coli citrate synthase variants having reduced activity was developed based initially on the increased generation of acid, observed visually by prolonged color change in the pH indicator bromocresol purple. Five hundred fifty‐two potential variants were isolated and each were cultured on glucose as sole carbon ...
Jeffrey K. Dodelin, Ronnie L. Fulton, Abigail E. Rose, Mark A. Eiteman   +3 more
wiley   +1 more source

Single-Stage Biosynthesis Of Poly(3-Hydroxybutyrate-co-4- Hydroxybutyrate) Using Cupriavidus sp. Usmaa1020 Via Mixed-Substrate Cultivation Strategy [PDF]

, 2017
Kopolimer poli(3-hidroksibutirat-ko-4-hidroksibutirat) [P(3HB-ko-4HB)] merupakan polihidroksialkanoat (PHA) yang penting dalam bidang biofarmaseutikal dan perubatan Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is ...
Huong, Kai Hee
core   +1 more source

Near‐infrared light‐activated aptamer‐based nanoprobe for spatiotemporally resolved detection of L‐lactate in colorectal cancer

BMEMat, EarlyView.
A near‐infrared (NIR) light‐activated “lock‐key” nanodevice is reported for spatiotemporally resolved detection of intratumoral L‐lactate. The system stays silent until deep‐penetrating NIR light remotely unlocks its function, allowing for precise sensing within tumors.
Siyu Pan, Xuanyi Lu, Wenjie Yang, Yunhui Peng, Lingfu Deng, Shuai Zha, Xueyang Fang, Guochen Bao, Lijun Jiang   +8 more
wiley   +1 more source

Microbial Synthesis and Characterization of Poly (3-Hydroxybutyrate-co- 4-Hydroxybutyrate) Copolymers [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2011
The research is focused on the prospective representative of the family of biodegradable polymers - polyhydroxyalkanoates (PHAs), the copolymer poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P(3HB-co-4HB).
Natalia O. Zhila, Tatiana G. Volova, Elena D. Nikolaeva, Daria A. Syrvacheva   +3 more
doaj  

Dilemma in Carotenoids Versus Polyhydroxyalkanoates (PHAs) Synthesis Using Haloarchaea as Cell Factories

Chemistry – A European Journal, EarlyView.
Production of PHAs by haloarchaea: the production of carotenoids and PHAs is concomitant, and consequently, various metabolic pathways compete for the carbon source. This results in a loss of PHA production efficiency. Efficient control of carbon source utilization (favoring certain metabolic pathways at the expense of others) is the key to the ...
Rosa María Martínez‐Espinosa
wiley   +1 more source