Results 111 to 120 of about 1,121,470 (291)

Mitochondrial Dysfunction in Propionic Acidemia: A Case‐Report and Review of the Literature

open access: yesJIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Propionic acidemia is an inborn error of metabolism involving an enzymatic defect of propionyl‐CoA carboxylase that results in the build‐up of toxic metabolites which can induce metabolic decompensation. Secondary mitochondrial dysfunction in propionic acidemia has been commonly recognized; however, its clinical presentation and management are
Brandon K. Walther   +5 more
wiley   +1 more source

The use of metabolic engineering to produce fatty acid-derived biofuel and chemicals in Saccharomyces cerevisiae: a review

open access: yesAIMS Bioengineering, 2016
Production of fatty acid-derived biofuels and chemicals have garnered attention in recent years owing to their potential to replace petroleum and plant oil-derived products. Through the metabolic engineering of the fatty acid metabolism pathway, advanced
Liwei Chen, Jaslyn Lee, Wei Ning Chen
doaj   +1 more source

Identification of Serum-Based Metabolic Feature and Characteristic Metabolites in Paraquat Intoxicated Mouse Models

open access: yesFrontiers in Physiology, 2020
Paraquat (PQ) is a widely used herbicide which can cause high mortality to humans. However, relatively few studies focus on metabolic feature of PQ intoxication for investigating the underlying mechanisms.
Youjia Yu   +16 more
doaj   +1 more source

Controlled biotechnological production of polyhydroxyalkanoates [PDF]

open access: yes, 2012
Předložená diplomová práce se zabývá produkcí polyhydroxyalkanoátů (PHA) bakterií Cupriavidus necator H16. Cílem práce byla příprava, selekce a charakterizace mutantních kmenů schopných vyšší produkce PHA.
Šnajdar, Ondřej
core  

Untargeted metabolomics of colonic digests reveals kynurenine pathway metabolites, dityrosine and 3-dehydroxycarnitine as red versus white meat discriminating metabolites [PDF]

open access: yes, 2016
Epidemiological research has demonstrated that the consumption of red meat is an important risk factor for the development of colorectal cancer (CRC), diabetes mellitus and cardiovascular diseases.
De Smet, S.   +5 more
core   +2 more sources

Alterations in Gut Microbiota and Metabolic Profiles in Relapsed or Refractory Lymphoma

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
Metabolomic volcano‐heatmap reveals seven upregulated metabolites in relapsed/refractory lymphoma, underscoring gut metabolic reprogramming as a potential therapeutic target. ABSTRACT To identify potential therapeutic strategies for relapsed or refractory lymphoma (R/RL) by examining differences in gut microbiota composition and metabolic profiles ...
Yu‐Ying Guo   +5 more
wiley   +1 more source

Enantioselective Microbial Reduction with Baker's Yeast on an Industrial Scale

open access: yesCHIMIA, 2000
Microbial synthesis is an important contribution to Green Chemistry and production-integrated environmental protection. The example of baker's yeast is used to demonstrate how microorganisms can be versatile reagents for asymmetric synthesis and
Martin Bertau, Martin Bürli
doaj   +2 more sources

The oxidation-reduction potential of coenzyme I [PDF]

open access: yes, 1940
The oxidation-reduction potential of cozymase (diphosphopyridine nucleotide) was calculated from the free energies of formation of aqueous d-alanine and d-glutamic acid based on thermal data, and the equilibria measured by Wurmser and Filitti-Wurmser(1 ...
Borsook, Henry
core  

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao   +4 more
wiley   +1 more source

Comparative Effects of Efavirenz and Dolutegravir on Metabolomic and Inflammatory Profiles, and Platelet Activation of People Living with HIV: A Pilot Study

open access: yesViruses
Antiretroviral therapy (ART) has reduced the mortality and morbidity associated with HIV. However, irrespective of treatment, people living with HIV remain at a higher risk of developing non-AIDS-associated diseases.
Crystal G. Roux   +5 more
doaj   +1 more source

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